P6762
Poly-L-aspartic acid sodium salt
mol wt 15,000-50,000
Synonym(s):
Poly(L-aspartic acid) sodium salt
mol wt
15,000-50,000
storage temp.
−20°C
SMILES string
NC(CC(O)=O)C(=O)O[Na]
Analysis Note
Molecular weight based on viscosity.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Nam Muk Oh et al.
Colloids and surfaces. B, Biointerfaces, 101, 298-306 (2012-09-27)
Advanced materials that have controllable pH-responsive properties when submerged in the lysosome have a great potential in intracellular drug delivery. We developed novel poly(L-amino acid) nanogels that were prepared by a facile cross-linking of poly[L-aspartic acid-g-(3-diethylaminopropyl)]-b-poly(ethylene glycol)-maleimide [poly(L-Asp-g-DEAP)-b-PEG-Mal] and poly(L-aspartic
Kyung Hyun Min et al.
Biomaterials, 33(23), 5788-5797 (2012-05-18)
A mineral (calcium phosphate, CaP)-reinforced core-shell-corona micelle was evaluated as a nanocarrier of doxorubicin (DOX) for cancer therapy. The polymer micelles of poly(ethylene glycol)-b-poly(L-aspartic acid)-b-poly(L-phenylalanine) (PEG-PAsp-PPhe) in the aqueous phase provided the three distinct functional domains: the hydrated PEG outer
Chao Li et al.
Bioconjugate chemistry, 23(9), 1832-1837 (2012-08-09)
Genome manipulation controlled by small metal complexes has attracted extensive interest because of their potential application in the fields of molecular biotechnology and drug development. However, their medicinal application is still limited due to the distinct toxicity of the free
Jihui Tang et al.
Die Pharmazie, 67(9), 756-764 (2012-09-29)
A novel block copolymer containing two polymeric components, poly(L-aspartic acid)-b-poly (L-phenylalanine) (PAA-PPA), was synthesized and its potential for the preparation of copolymer micelles with a poorly water-soluble drug was investigated in this study. The chemical structure and physical properties of
Loredana E Nita et al.
Colloids and surfaces. B, Biointerfaces, 103, 544-549 (2012-12-25)
Pluronic F127/poly(aspartic acid) mixtures were investigated in dilute solutions by viscometry and dynamic light scattering. The two polymers were chosen due to well known applications in biomedical field, taking into account the final purpose (the use of the complex structure
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