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Merck
CN

P7627

6-Phosphogluconic acid barium salt hydrate

Grade VI, ≥90%, powder

Synonym(s):

6-PG-Ba, D-Gluconate 6-phosphate barium salt

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About This Item

Empirical Formula (Hill Notation):
C6H10Ba1.5O10P · xH2O
CAS Number:
921-62-0
Molecular Weight:
479.10 (anhydrous basis)
NACRES:
NA.25
PubChem Substance ID:
24898864
UNSPSC Code:
12352201
EC Number:
213-069-9
Beilstein/REAXYS Number:
1729373

Key Documents

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biological source

synthetic (organic)

type

Grade VI

assay

≥90%

form

powder

color

white

storage temp.

−20°C

SMILES string

[O-]P(OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O)([O-])=O.[H]O[H].C

InChI

1S/C6H13O10P.CH4.H2O/c7-2(1-16-17(13,14)15)3(8)4(9)5(10)6(11)12;;/h2-5,7-10H,1H2,(H,11,12)(H2,13,14,15);1H4;1H2/p-3/t2-,3-,4+,5-;;/m1../s1

InChI key

VINGHIAQWNFZIR-ZBHRUSISSA-K

General description

suitable for glucose-6-phosphate dehydrogenase tests

Application

6-Phosphogluconic acid has been used in a study to assess the biochemistry of Coxiella burnetti. It has also been used in a study to investigate the enzymatic transfer of hydrogen.

Preparation Note

Prepared by a modification of the procedure of Seegmiller, J.E., et al., J. Biol. Chem., 192, 175 (1951).

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCC5050
SLBZ8733
SLBP7427V
019K37851V
019K37851

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N Takahashi et al.
Journal of dental research, 89(12), 1383-1388 (2010-10-07)
Dental caries is initiated by demineralization of the tooth surface through acid production by sugar metabolism of supragingival plaque microflora. To elucidate the sugar metabolic system, we used CE-MS to perform metabolomics of the central carbon metabolism, the EMP pathway
Francisco Velázquez et al.
Journal of bacteriology, 186(24), 8267-8275 (2004-12-04)
Glucose and other C sources exert an atypical form of catabolic repression on the sigma54-dependent promoter Pu, which drives transcription of an operon for m-xylene degradation encoded by the TOL plasmid pWW0 in Pseudomonas putida. We have used a genetic
The enzymatic transfer of hydrogen. IX. The reactions catalyzed by glucose 6-phosphate dehydrogenase and 6-phosphogluconic dehydrogenase.
B K STERN et al.
The Journal of biological chemistry, 235, 205-208 (1960-01-01)
Stefania Hanau et al.
The Journal of biological chemistry, 285(28), 21366-21371 (2010-05-11)
The reductive carboxylation of ribulose-5-phosphate (Ru5P) by 6-phosphogluconate dehydrogenase (6PGDH) from Candida utilis was investigated using kinetic isotope effects. The intrinsic isotope effect for proton abstraction from Ru5P was found at 4.9 from deuterium isotope effects on V and V/K
Lei Li et al.
The Journal of biological chemistry, 281(35), 25568-25576 (2006-06-29)
The 6-phosphate of 6-phosphogluconate (6PG) is proposed to anchor the sugar phosphate in the active site and aid in orientating the substrate for catalysis. In order to test this hypothesis, alanine mutagenesis was used to probe the contribution of residues
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Global Trade Item Number

SKUGTIN
P7627-1G04061834395515
P7627-500MG04061832392585
P7627-100MG04061834395485

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