P8179
Pro-Thr-Pro-Ser amide
≥97% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C17H29N5O6
CAS Number:
Molecular Weight:
399.44
UNSPSC Code:
12352200
MDL number:
assay
≥97% (HPLC)
storage temp.
−20°C
SMILES string
CC(O)C(NC(=O)C1CCCN1)C(=O)N2CCCC2C(=O)NC(CO)C(N)=O
Biochem/physiol Actions
Inhibits proteolysis of IgA by Neisseria gonorrheae protease type I
Other Notes
Analog of the hinge region of human IgA2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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S G Wood et al.
Journal of medicinal chemistry, 32(10), 2407-2411 (1989-10-01)
The six series of unique tetrapeptides and their blocked N-acetyl, C-amide, and N-acetyl-C-amide analogues which comprise the hinge region of human IgA1 (Ser224 to Ser240) have been synthesized and tested as inhibitors of the type 1 IgA1 proteinase elaborated by
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