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S112

(S)-(−)-Sulpiride

Name: (<I>S</I>)-(−)-Sulpiride
Brand: SIGMA

Synonym(s):

(S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide, Levosulpiride

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₂₃N₃O₄S

CAS Number:

23672-07-3

Molecular Weight:

341.43

UNSPSC Code:

12352200

MDL number:

MFCD00055220

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technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

183-186 °C (lit.)

application(s)

forensics and toxicology
veterinary

SMILES string

CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O

InChI

1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1

InChI key

BGRJTUBHPOOWDU-NSHDSACASA-N

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Biochem/physiol Actions

D₂ dopamine receptor antagonist; antipsychotic.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

108H4745

048H10931

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Hypolipidemic and weight reducing activity of the ethanolic extract of Tamarindus indica fruit pulp in cafeteria diet- and sulpiride-induced obese rats.

Vaneeta Jindal et al.

Journal of pharmacology & pharmacotherapeutics, 2(2), 80-84 (2011-07-21)

To investigate the effect of ethanolic extract of fruit pulp of Tamarindus indica Linn. (Family: Caesalpiniaceae) on obesity in rats using cafeteria diet-induced obesity and antipsychotic drug (sulpiride)-induced obesity. Cafeteria dietwas administered for 40 successive days to male Wistar rats

Light-dependent translocation of arrestin in rod photoreceptors is signaled through a phospholipase C cascade and requires ATP.

Wilda Orisme et al.

Cellular signalling, 22(3), 447-456 (2009-11-06)

Partitioning of cellular components is a critical mechanism by which cells can regulate their activity. In rod photoreceptors, light induces a large-scale translocation of arrestin from the inner segments to the outer segments. The purpose of this project is to

Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors.

José M Entrena et al.

Psychopharmacology, 205(1), 21-33 (2009-03-28)

We evaluated the effects of haloperidol and its metabolites on capsaicin-induced mechanical hypersensitivity (allodynia) and on nociceptive pain induced by punctate mechanical stimuli in mice. Subcutaneous administration of haloperidol or its metabolites I or II (reduced haloperidol) dose-dependently reversed capsaicin-induced

Global Trade Item Number

SKU	GTIN
SAB5700281-100UL	04065265172264
SAB5701848-100UL	04065267676227
SAB1413215-20UL	04065265467346

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