S6635
Span® 20
Synonym(s):
Sorbitan laurate, Sorbitan monolaurate
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About This Item
CAS Number:
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161900
EC Number:
215-663-3
MDL number:
description
non-ionic
mol wt
346.47 g/mol
greener alternative product characteristics
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.
sustainability
Greener Alternative Product
concentration
≥44% (GC)
greener alternative category
, Aligned
SMILES string
CCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O
InChI
1S/C18H34O6/c1-2-3-4-5-6-7-8-9-10-11-16(21)23-13-15(20)18-17(22)14(19)12-24-18/h14-15,17-20,22H,2-13H2,1H3/t14-,15?,17+,18+/m0/s1
InChI key
LWZFANDGMFTDAV-WYDSMHRWSA-N
General description
Span 20 is a co-surfactant.
We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is 100% bio-based non-ionic surfactant, thus aligns with "Use of Renewable Feedstocks" and belongs to "12 principles aligned" category of our greener alternatives.
Application
Span 20 has been used in a study to assess enhanced solubility and oral bioavailability of itraconazole. It has also been used in a study to investigate the oxidation of unsaturated lipids in oil-in-water emulsions.
Other Notes
Fatty acid composition: Lauric acid (C12:0) ≥ 44%; balance primarily myristic (C14:0), palmitic (C16:0) and linolenic (C18:3) acids.
Legal Information
Span is a registered trademark of Croda International PLC
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
>300.2 °F - closed cup
flash_point_c
> 149 °C - closed cup
ppe
Eyeshields, Gloves, type N95 (US)
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Claire Berton et al.
Journal of colloid and interface science, 377(1), 244-250 (2012-04-25)
The development of lipid oxidation in oil-in-water (O/W) emulsions is widely influenced by the properties of the interfacial layer, which separates the oil and water phases. In this work, the effect of the structure of the interface on the oxidative
Orapan Paecharoenchai et al.
Journal of drug targeting, 20(9), 783-792 (2012-08-31)
Non-ionic surfactant-based vesicles (niosomes) composed of non-ionic surfactants (i.e., Tween and Span) and cholesterol were formulated, and their turbidity and particle size assayed. The most appropriate niosomes formulation was mixed with novel synthesized spermine-based cationic lipids to prepare cationic niosomes
Gabriela Calderó et al.
Journal of colloid and interface science, 353(2), 406-411 (2010-10-26)
Formation of polymeric O/W nano-emulsions has been studied in the water/polyoxyethylene 4 sorbitan monolaurate/ethylcellulose solution system by the phase inversion composition (PIC) method. These nano-emulsions were used for the preparation of nanoparticles by solvent evaporation. Composition variables such as O/S
Global Trade Item Number
| SKU | GTIN |
|---|---|
| S6635-1L | 04061836959494 |
| S6635-250ML | 04061837609367 |