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Merck
CN

SML0032

Triacetyl resveratrol

≥98% (HPLC)

Synonym(s):

3,5,4′-Tri-O-acetylresveratrol, 5-[(1E)-2-[4-(acetyloxy)phenyl]ethenyl]-1,3-Benzenediol-1,3-diacetate

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About This Item

Empirical Formula (Hill Notation):
C20H18O6
CAS Number:
Molecular Weight:
354.35
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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Quality Level

assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

white to tan

solubility

DMSO: ≥18 mg/mL

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

room temp

SMILES string

CC(=O)Oc1ccc(cc1)\C=C\c2cc(OC(C)=O)cc(OC(C)=O)c2

InChI

1S/C20H18O6/c1-13(21)24-18-8-6-16(7-9-18)4-5-17-10-19(25-14(2)22)12-20(11-17)26-15(3)23/h4-12H,1-3H3/b5-4+

InChI key

PDAYUJSOJIMKIS-SNAWJCMRSA-N

General description

Resveratrol (RSV) is a natural polyphenolic antioxidant.

Biochem/physiol Actions

Resveratrol prodrug. SIRT inhibitor
Resveratrol (RSV) plays a protective role on the nervous and cardiovascular systems. It is considered as a modulator of energetic metabolism as it controls glucose homeostasis in obese mice, improves fatty acid oxidation (FAO) and promotes the expression of genes that participate in mitochondrial biogenesis.
Resveratrol prodrug. SIRT inhibitor
Triacetyl resveratrol displays superior bioavailability to the parent compound, resveratrol. The compound induces p53 activity and inhibits proliferation in breast and prostate tumor cell lines.


Storage Class

11 - Combustible Solids

wgk

WGK 3

Regulatory Information

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Resveratrol induces a mitochondrial complex I dependent increase in NADH oxidation responsible for sirtuin activation in liver cells.
Desquiret-Dumas V, et al.
The Journal of Biological Chemistry, 2013 (2013)
Liqiong Ding et al.
Biochemical pharmacology, 171, 113691-113691 (2019-11-11)
Resveratrol is a natural compound found in many plant species that has broad therapeutic benefits. Here, we investigated the effects of resveratrol on the replication of HSV-2. We found that resveratrol accelerated replication of HSV-2 and increased release of progeny
Tammy R Dugas et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 107(3), 646-651 (2018-08-10)
Peripheral artery disease is a cardiovascular disease characterized by a narrowing of arteries that supply blood to the extremities, particularly, the legs. When surgical intervention is warranted, the primary approach is balloon angioplasty. Drug coated balloons (DCB) designed to release



Global Trade Item Number

SKUGTIN
SML0032-10MG04061837076596
SML0032-50MG04061833221600