T4446
N-Acetyl-L-tyrosine
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About This Item
Linear Formula:
4-(HO)C6H4CH2CH(NHCOCH3)CO2H
CAS Number:
Molecular Weight:
223.23
EC Number:
208-671-3
UNSPSC Code:
12352209
NACRES:
NA.26
Beilstein/REAXYS Number:
2697172
MDL number:
biological source
non-animal source
assay
≥98.5%
form
crystalline powder
manufacturer/tradename
Ajinomoto
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, heavy metals, tested
mp
149-152 °C (lit.)
solubility
H2O: 25 mg/mL
application(s)
pharmaceutical (small molecule)
SMILES string
CC(=O)N[C@@H](Cc1ccc(O)cc1)C(O)=O
InChI
1S/C11H13NO4/c1-7(13)12-10(11(15)16)6-8-2-4-9(14)5-3-8/h2-5,10,14H,6H2,1H3,(H,12,13)(H,15,16)/t10-/m0/s1
InChI key
CAHKINHBCWCHCF-JTQLQIEISA-N
General description
To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to documentation for this product requires a confidentiality disclosure agreement.
Application
L-Tyrosine is a non-essential amino acid. It can be used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. N-Acetyl-L-tyrosine is an acetylated derivative of the essential amino acid L-tyrosine with reported improved nutritional properties.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Wei Xie et al.
Journal of inorganic biochemistry, 103(1), 58-63 (2008-10-25)
Complexes of the uranyl cation [UO(2)(2+)] with histidine (His), N-acetyl-histidine (NAH), tyrosine (Tyr), and N-acetyl-tyrosine (NAT) were studied by UV-visible and NMR spectroscopy, and by potentiometric titration. Protonation constants for each ligand are reported, as are cumulative formation constants for
A Rescigno et al.
Biochimica et biophysica acta, 1384(2), 268-276 (1998-07-11)
Tyrosinase is a copper containing protein which catalyzes the hydroxylation of monophenols and the oxidation of diphenols to o-quinones. The monophenolase activity of tyrosinase is characterized by a typical lag time. In this paper the influence of 3-hydroxyanthranilic acid on
Investigation of DNA-protein cross-link formation between lysozyme and oxanine by mass spectrometry.
Hauh-Jyun Candy Chen et al.
Chembiochem : a European journal of chemical biology, 9(7), 1074-1081 (2008-03-21)
Reactive nitrogen species are implicated in inflammatory diseases and cancers. Oxanine (Oxa) is a DNA lesion product originating from the guanine base through exposure to nitric oxide, nitrous acid, or N-nitrosoindoles. Oxanine was found to mediate formation of DNA-protein cross-links
Global Trade Item Number
| SKU | GTIN |
|---|---|
| T4446-100G | 04061837346125 |
| T4446-1KG | 04061834417507 |
| T4446-25KG | 04061834432630 |
| T4446-10KG | 04061834432623 |