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Merck
CN

T5566

TAPSO

Biotechnology Performance Certified, suitable for cell culture, ≥99% (titration)

Synonym(s):

2-Hydroxy-3-[tris(hydroxymethyl)methylamino]-1-propanesulfonic acid, N-[Tris(hydroxymethyl)methyl]-3-amino-2-hydroxypropanesulfonic acid

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About This Item

Empirical Formula (Hill Notation):
C7H17NO7S
CAS Number:
68399-81-5
Molecular Weight:
259.28
UNSPSC Code:
12161700
PubChem Substance ID:
24900299
EC Number:
269-993-8
Beilstein/REAXYS Number:
2113949

Key Documents

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grade

Biotechnology Performance Certified

assay

≥99% (titration)

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin and bioburden, tested

useful pH range

7.0-8.2

pKa (25 °C)

7.6

cation traces

heavy metals (as Pb): ≤5 ppm

foreign activity

DNase, RNase, protease, none detected

SMILES string

OCC(CO)(CO)NCC(O)CS(O)(=O)=O

InChI

1S/C7H17NO7S/c9-3-7(4-10,5-11)8-1-6(12)2-16(13,14)15/h6,8-12H,1-5H2,(H,13,14,15)

InChI key

RZQXOGQSPBYUKH-UHFFFAOYSA-N

Disclaimer

According to Ferreira, et al., TAPSO can have a strong interaction with iron in solution. Based on this citation, it is recommended to use plastic-coated or PTFE-coated utensils when working with this chemical.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
089H5414

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(Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review.
Ferreira C.M.H. et al.
Royal Society of Chemistry Advances, 5, 30989-31003 (2015)
(Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions ? a review.
Ferreira, C.M.H., et al.
Royal Society of Chemistry Advances, 5, 30989-31003 (2015)

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