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Merck
CN

T5905

L-Thyronine

≥98.0% (TLC)

Synonym(s):

3-(p-[p-Hydroxyphenoxy]phenyl)-L-alanine

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About This Item

Empirical Formula (Hill Notation):
C15H15NO4
CAS Number:
Molecular Weight:
273.28
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
216-483-8
MDL number:
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Product Name

L-Thyronine,

assay

≥98.0% (TLC)

form

powder

SMILES string

N[C@@H](Cc1ccc(Oc2ccc(O)cc2)cc1)C(O)=O

InChI

1S/C15H15NO4/c16-14(15(18)19)9-10-1-5-12(6-2-10)20-13-7-3-11(17)4-8-13/h1-8,14,17H,9,16H2,(H,18,19)/t14-/m0/s1

InChI key

KKCIOUWDFWQUBT-AWEZNQCLSA-N



Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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J Köhrle
Cellular and molecular life sciences : CMLS, 57(13-14), 1853-1863 (2001-02-24)
Thyroid hormones control growth, development, differentiation and metabolism in vertebrates. Most of the actions of the active thyroid hormone T3 (3,5,3'-triiodo-L-thyronine) are exerted via ligand-activated nuclear T3 receptors. Activation of the secretory product of the thyroid gland, L-thyroxine (3,3',5,5'-tetraiodo-L-thyronine), or
J S LoPresti et al.
The Journal of clinical endocrinology and metabolism, 70(5), 1479-1484 (1990-05-01)
A hidden pool of rT3 production represents a source of rT3 that is minimally reflected in circulating rT3 levels. To test for the existence of such a source of rT3 production in man, varying doses of the generalized deiodinase inhibitor
I J Chopra et al.
The Journal of clinical endocrinology and metabolism, 75(1), 189-194 (1992-07-01)
A highly sensitive, specific, and reproducible RIA has been developed to measure T3 sulfate (T3S). Only T4 sulfate cross-reacted significantly (approximately 3%) in the RIA; rT3 sulfate, T4, T3, rT3, and diiodothyronine cross-reacted less than 0.01%. T3S was bound by



Global Trade Item Number

SKUGTIN
T5905-500MG04061832727066