Skip to Content
Merck
CN

T6381

N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane

with 1% trimethylchlorosilane, derivatization grade (GC derivatization), LiChropur™

Synonym(s):

BSTFA + TMCS

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
CF3C[=NSi(CH3)3]OSi(CH3)3
CAS Number:
25561-30-2
Molecular Weight:
257.40
UNSPSC Code:
23151817
NACRES:
NA.22
PubChem Substance ID:
24900370
MDL number:
MFCD00008269
Beilstein/REAXYS Number:
2050024

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

grade

derivatization grade (GC derivatization)

Quality Level

100

quality

LiChropur™, with 1% trimethylchlorosilane

contains

1% trimethylchlorosilane as additive

reaction suitability

reagent type: derivatization reagent
reaction type: Silylations

technique(s)

gas chromatography (GC): suitable

color

hazy clear to colorless

refractive index

n20/D 1.384 (lit.)

bp

45-50 °C/14 mmHg (lit.)

solubility

hexane: miscible 100 mg/mL

density

0.97 g/mL (lit.)

storage temp.

2-8°C

SMILES string

C[Si](C)(C)O\C(=N\[Si](C)(C)C)C(F)(F)F

InChI

1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3/b12-7+

InChI key

XCOBLONWWXQEBS-KPKJPENVSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane is a silylating reagent generally used in estrogenic steroid hormone identification and quantification.

Application

BSTFA+TMCS has been used as derivatizing reagent for GC-MS determination of natural and synthetic estrogenic steroids.

Packaging

Clear borosilicate glass, high hydrolytic resistance (Type I)
Sealed ampules contain 1 ml. Gram sizes are in screw-cap bottles.

Other Notes

The position of the silyl groups has not been unequivocally established. It has been referred to as both N,N and N,O.

Legal Information

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

44.1 °F - closed cup

flash_point_c

6.7 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

Regulatory Information

危险化学品

This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000540399
BCCP5473
0000540399
0000433390
0000433390

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Pitfalls and solution for simultaneous determination of estrone and 17a-ethinylestradiol by gas chromatography?mass spectrometry after derivatization with N, O-bis (trimethylsilyl) trifluoroacetamide.
Zhang, Kai, and Yuegang Zuo.
Analytica Chimica Acta, 554.1, 190-196 (2005)
Shabtai Cohen et al.
Plants (Basel, Switzerland), 9(9) (2020-08-23)
Emerging needs for diversifying human diet and to explore novel therapeutic procedures have led to increasing attempts to retrieve traditional nourishments and recruit beneficial wild plant species. Species of the genus Erodium (Geraniaceae) harbor medicinal indications and substances known from
Ahmed I Rushdi et al.
SpringerPlus, 3, 253-253 (2014-06-14)
Propolis is a sticky material mixed by honeybees to utilize it in protecting their hives from infection by bacteria and fungi. The therapeutic properties of propolis are due to its chemical composition with bio-active compounds; therefore, researchers are interested in
Hidenori Matsukami et al.
The Science of the total environment, 493, 672-681 (2014-07-06)
Chlorinated and non-halogenated organophosphorus flame retardants (OPFRs) including tris(2-chloroisopropyl) phosphate (TCIPP), diethylene glycol bis(di(2-chloroisopropyl) phosphate) (DEG-BDCIPP), triphenyl phosphate (TPHP), and bisphenol A bis(diphenyl phosphate) (BPA-BDPP) have been used increasingly as alternatives to polybrominated diphenyl ethers and other brominated flame retardants.
Nyi Nyi Naing et al.
Journal of chromatography. A, 1423, 1-8 (2015-11-05)
Electro membrane extraction-solid-liquid phase microextraction (EME-SLPME) was developed for the first time to determine phenolic contaminants in water. The extraction system consisted of a solid/liquid interface that permitted a three-phase microextraction approach involving an aqueous sample (donor phase): an organic
View All Related Papers

Related Content

Product Information Sheet - T6381

Product Information Sheet

Global Trade Item Number

SKUGTIN
T6381-1AMP04061837688652
T6381-100G04061837688638
T6381-10AMP04061837688645
T6381-25G04061837688676
T6381-5G04061837688683

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service