T7029
Thionin acetate salt
certified by the BSC
Synonym(s):
3,7-Diamino-5-phenothiazinium acetate, Lauth’s violet
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About This Item
Empirical Formula (Hill Notation):
C12H9N3S · C2H4O2
CAS Number:
Molecular Weight:
287.34
UNSPSC Code:
12171500
PubChem Substance ID:
MDL number:
Colour Index Number:
52000
Beilstein/REAXYS Number:
4345073
agency
certified by the BSC
composition
Dye content, ≥85%
SMILES string
CC([O-])=O.Nc1ccc2nc3ccc(N)cc3[s+]c2c1
InChI
1S/C12H10N3S.C2H4O2/c13-7-1-3-9-11(5-7)16-12-6-8(14)2-4-10(12)15-9;1-2(3)4/h1-6H,13-14H2;1H3,(H,3,4)/q+1;/p-1
InChI key
OWXBIRAFHWASMS-UHFFFAOYSA-M
Application
Certified for use in Churukian-Schenk thionine method; Stoughton′s method for plant material.
For use as a general nuclear stain for chromatin and mucin; for staining Nissl granules by end-point buffering and for showing malignant cells in frozen biopsy sections; and as a stain for semi-thin sections of plant material for light microscopy.
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Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Agustina Cabral et al.
Molecular metabolism, 32, 69-84 (2020-02-08)
Arcuate nucleus (ARC) neurons producing Agouti-related peptide (AgRP) and neuropeptide Y (NPY; ARCAgRP/NPY neurons) are activated under energy-deficit states. ARCAgRP/NPY neurons innervate the hypothalamic paraventricular nucleus (PVH), and ARC→PVH projections are recognized as key regulators of food intake. Plasma ghrelin
Yunying Xie et al.
Analytica chimica acta, 699(1), 44-48 (2011-06-28)
We reported a graphene-based immunosensor for electrochemical quantification of phosphorylated p53 on serine 15 (phospho-p53(15)), a potential biomarker of gamma-radiation exposure. The principle is based on sandwich immunoassay and the resulting immunocomplex is formed among phospho-p53 capture antibody, phospho-p53(15) antigen
Selvaraj Baskar et al.
Biosensors & bioelectronics, 33(1), 95-99 (2012-01-24)
We report here a novel detection scheme for simultaneous detection of NADH and H(2)O(2) based on a bifunctional poly(thionine)-modified electrode. Electropolymerization of thionine on a "preanodized" screen-printed carbon electrode effectively lowers the oxidation potential of NADH to 0.15 V (vs.