Skip to Content
Merck
CN

T8877

2,3,5-Triphenyltetrazolium chloride

≥98.0% (HPLC)

Synonym(s):

TPTZ, TTZ, Tetrazolium Red

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C19H15ClN4
CAS Number:
298-96-4
Molecular Weight:
334.80
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
24900566
EC Number:
206-071-6
Beilstein/REAXYS Number:
3923356
MDL number:
MFCD00011963

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Quality Level

200

assay

≥98.0% (HPLC)

form

powder

color

faintly yellow

solubility

H2O: 50 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

2-8°C

SMILES string

[Cl-].c1ccc(cc1)-c2nn(-c3ccccc3)[n+](n2)-c4ccccc4

InChI

1S/C19H15N4.ClH/c1-4-10-16(11-5-1)19-20-22(17-12-6-2-7-13-17)23(21-19)18-14-8-3-9-15-18;/h1-15H;1H/q+1;/p-1

InChI key

PKDBCJSWQUOKDO-UHFFFAOYSA-M

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

2,3,5-Triphenyltetrazolium chloride is a colorless water-soluble dye. In the mitochondria of living cells, it is reduced to a deep red, water-insoluble compound (formazan). 2,3,5-Triphenyltetrazolium chloride helps to distinguish between viable and infarcted brain tissue after stroke.

Application

2,3,5-Triphenyltetrazolium chloride has been used to stain heart tissue to measure the extent of acute lesion. It has also been used to stain brain tissue to check the size of infarct area.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Sol. 1 - Skin Irrit. 2

Storage Class

4.1B - Flammable solid hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCCP1728
BCCN9241
BCCN7479
BCCN1039
BCCM7392

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Chesarahmia Dojo Soeandy et al.
Apoptosis : an international journal on programmed cell death, 24(7-8), 578-595 (2019-05-11)
Over the past 30 years a number of animal models of cerebral ischemic injury have been developed. Middle cerebral artery occlusion (MCAO) in particular reproduces both ischemic and reperfusion elements and is widely utilized as a model of ischemic stroke in
Human umbilical mesenchymal stem cells promote recovery after ischemic stroke.
Lin YC et al.
Stroke, 42, 2045-2045 (2011)
Evaluation of a novel epicardial atrial fibrillation treatment system.
Kiser AC et al.
The Annals of Thoracic Surgery, 85, 300-300 (2008)
Mannitol-facilitated perfusion staining with 2,3,5-triphenyltetrazolium chloride (TTC) for detection of experimental cerebral infarction and biochemical analysis.
Sun YY et al.
Journal of Neuroscience Methods, 203, 122-122 (2012)
Jia Huang et al.
Journal of molecular and cellular cardiology, 134, 107-118 (2019-07-14)
Myocardial ischemia/reperfusion (I/R) injury is the major limitation for the cardioprotective action of revascularization after myocardial infarction. Lymphocyte adapter protein (Lnk), an adapter protein, has a regulatory role in multiple signaling pathways by functioning as a scaffold for different substrates.
View All Related Papers

Global Trade Item Number

SKUGTIN
T8877-25G04061835349296
T8877-100G04061835349272
T8877-10G04061835349289
T8877-50G04061835349302
T8877-5G04061835349319

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service