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Merck
CN

U7129

Urea solution

40 % (w/v) in H2O

Synonym(s):

Carbamide, Carbonyldiamide

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About This Item

Linear Formula:
NH2CONH2
CAS Number:
57-13-6
Molecular Weight:
60.06
UNSPSC Code:
12352111
NACRES:
NA.75
PubChem Substance ID:
24900664
MDL number:
MFCD00008022
Beilstein/REAXYS Number:
635724

Key Documents

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sterility

non-sterile; sterile-filtered

Quality Level

100

contains

0.1% benzoic acid as preservative

packaging

vial of 5 mL

concentration

40 % (w/v) in H2O

storage temp.

2-8°C

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

human ... CA1(759), CA2(760), EPHX2(2053)
mouse ... Ephx2(13850)
rat ... Ppm1a(24666)

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Application

Recommended for the detection of urease activity.

Biochem/physiol Actions

Urea solution is primarily used for protein denaturation. It also increases solubility of hydrocarbons and reduce micelle formation. Urea solution at high concentration leads to the destabilization of amyloid β16−22 oligomers.

Preparation Note

Warm the refrigerated 40% urea solution to room temperature. Aseptically add 5 mL to 95 mL of sterile molten Urea Agar Base (Christensen). Mix well and dispense in sterile tubes.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX2505
MKBZ0172V
MKBX6844V
MKBW9254V
MKBW2754V

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Aqueous urea solutions: structure, energetics, and urea aggregation
Stumpe MC, et al.
The Journal of Physical Chemistry B, 111(22), 6220-6228 (2007)
L Li et al.
Cell death and differentiation, 22(7), 1081-1093 (2014-12-20)
P53 is critically important in preventing oncogenesis but its role in inflammation in general and in the function of inflammatory macrophages in particular is not clear. Here, we show that bone marrow-derived macrophages exhibit endogenous p53 activity, which is increased
G L French et al.
Lancet (London, England), 2(8551), 117-119 (1987-07-18)
Tuberculostearic acid, a structural component of Mycobacterium tuberculosis, was identified by gas chromatography/mass spectrometry with selected ion monitoring in cerebrospinal fluid (CSF) from 13 patients with proven and 8 out of 9 patients with suspected tuberculous meningitis; the negative result
A mechanically and electrically self-healing supercapacitor.
Hua Wang et al.
Advanced materials (Deerfield Beach, Fla.), 26(22), 3638-3643 (2014-02-21)
Sreenivasa C Ramaiahgari et al.
Archives of toxicology, 88(5), 1083-1095 (2014-03-07)
Immortalized hepatocyte cell lines show only a weak resemblance to primary hepatocytes in terms of gene expression and function, limiting their value in predicting drug-induced liver injury (DILI). Furthermore, primary hepatocytes cultured on two-dimensional tissue culture plastic surfaces rapidly dedifferentiate
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Related Content

Global Trade Item Number

SKUGTIN
U7129-1VL04061837410093

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