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A0263

Sigma-Aldrich

Aflatoxin G2

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Empirical Formula (Hill Notation):
C17H14O7
CAS Number:
7241-98-7
Molecular Weight:
330.29
Beilstein:
1692017
EC Number:
230-643-4
MDL number:
MFCD00078141
PubChem Substance ID:
24890416
NACRES:
NA.77

form

powder

Quality Level

200

storage temp.

2-8°C

SMILES string

[H][C@@]12CCO[C@]1([H])Oc3cc(OC)c4C5=C(C(=O)OCC5)C(=O)Oc4c23

InChI

1S/C17H14O7/c1-20-9-6-10-12(8-3-5-22-17(8)23-10)14-11(9)7-2-4-21-15(18)13(7)16(19)24-14/h6,8,17H,2-5H2,1H3/t8-,17+/m0/s1

InChI key

WPCVRWVBBXIRMA-WNWIJWBNSA-N

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General description

Aflatoxin G2 is a fungal secondary toxic metabolite synthesized by Aspergillus parasiticus, Aspergillus flavus, and Aspergillus nomius, species that are found in tropical and subtropical regions of the world. Aflatoxin Gs (AFGs) are derivatives of difuranocoumarin and contain a bifuran group linked to a coumarin nucleus and a lactone ring.

Application

Aflatoxin G2 has been used as a standard to estimate the levels of aflatoxins by immunoaffinity column cleanup in:
  • peanut confection
  • Ginseng and other roots
  • olive oil, peanut oil, and sesame oil

Biochem/physiol Actions

Aflatoxins are hepatocarcinogenic and act as food contaminants in peanuts, fruits, cereals, corn, and dry fruits.

Warning

Possibly carcinogenic.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Acute Tox. 2 Inhalation - Carc. 1B - Muta. 1B

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

高风险级别生物产品--毒素类产品

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Mary Trucksess et al.
Journal of AOAC International, 89(3), 624-630 (2006-06-24)
Mycotoxins are toxic secondary metabolites produced by certain molds and are common contaminants of many important food crops, such as grains, nuts, and spices. Some mycotoxins are found in fruits, vegetables, and botanical roots. These contaminants have a broad range
Dipendra K Mahato et al.
Frontiers in microbiology, 10, 2266-2266 (2019-10-23)
Aflatoxins produced by the Aspergillus species are highly toxic, carcinogenic, and cause severe contamination to food sources, leading to serious health consequences. Contaminations by aflatoxins have been reported in food and feed, such as groundnuts, millet, sesame seeds, maize, wheat
Evaluation and improvement of extraction methods for the analysis of aflatoxins B1, B2, G1 and G2 from naturally contaminated maize
Bertuzzi T, et al.
Food Analytical Methods, 512-519 (2012)
Meritxell Ventura et al.
Journal of chromatography. A, 1048(1), 25-29 (2004-09-30)
An easy method for the determination of aflatoxins B1, G1, B2 and G2 in Rhammus purshiana by LC coupled to mass spectrometry has been developed. Aflatoxins were extracted with a mixture of methanol and water and then it was purified
Maria Helena Iha et al.
Journal of chromatography. A, 1483, 1-7 (2017-01-09)
The aim of this study was to investigate the feasibility of using multitime-regenerated immunoaffinity column (IAC) for aflatoxins B1, B2, G1 and G2 in peanut confection. After each use, the IAC was washed immediately with phosphate-buffered saline and stored for >12h
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