A1976
Anti-Amyloid Peptide β, Cleavage Site 42 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-Aβ 42
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
DB, ELISA (i), IHC, IP, RIA
Citations:
3
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen 4 kDa
species reactivity
rat, human, mouse
packaging
antibody small pack of 25 μg
technique(s)
dot blot: 0.05-1 μg/mL, immunoblotting: suitable, immunohistochemistry: suitable, immunoprecipitation (IP): suitable, indirect ELISA: 1:200, radioimmunoassay: 1:200
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
target post-translational modification
proteolytically cleaved (Ala42)
Gene Information
human ... APP(351)
mouse ... App(11820)
rat ... App(54226)
General description
Proteolytic cleavage of the amyloid precursor protein (APP) produces the small fragment amyloid β peptide. Cleavage of APP occurs mostly at residue 40 but to a lesser extent residue 42. Aggregates of amyloid β peptide are found deposited in the brains of Alzheimer′s patients.
Rabbit anti-amyloid peptide β, cleavage site 42 (Aβ42) antibody binds to human, mouse and rat Aβ42.
Immunogen
synthetic peptide of approximately 10 amino acid residues at the C-terminus of Aβ42.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Immunohistochemistry (1 paper)
Rabbit anti-Aβ42 is suitable for use in immunoblot, immunohistochemistry, immunoprecipitation, RIA, ELISA and dot blot applications.
Physical form
Solution in phosphate buffer, pH 7.4, containing approximately 25 μg of antibody.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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