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Merck
CN

A9758

ACES

≥99.0% (titration)

Synonym(s):

2-[(2-Amino-2-oxoethyl)azaniumyl]ethanesulfonate, 2-[(Carbamoylmethyl)amino]ethane-1-sulfonic acid, N-(2-Acetamido)-2-aminoethanesulfonic acid, N-(Carbamoylmethyl)-2-aminoethanesulfonic acid, N-(Carbamoylmethyl)taurine

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About This Item

Linear Formula:
H2NCOCH2NHCH2CH2SO3H
CAS Number:
Molecular Weight:
182.20
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
EC Number:
230-908-4
Beilstein/REAXYS Number:
2253770
MDL number:
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Quality Segment

assay

≥99.0% (titration)

form

crystalline powder

pH

3.0-4.5

useful pH range

6.1-7.5

pKa (25 °C)

6.8

mp

>220 °C (dec.) (lit.)

solubility

water: 0.523 g/mL, clear, colorless

application(s)

diagnostic assay manufacturing

storage temp.

room temp

SMILES string

NC(=O)CNCCS(O)(=O)=O

InChI

1S/C4H10N2O4S/c5-4(7)3-6-1-2-11(8,9)10/h6H,1-3H2,(H2,5,7)(H,8,9,10)

InChI key

DBXNUXBLKRLWFA-UHFFFAOYSA-N

General description

N-(2-Acetamido)-2-aminoethanesulfonic acid (ACES) is a zwitterionic buffer used in biochemistry and molecular biology research. It is one of the Good′s buffers with a pH range of 6.15 - 8.35. The preferred range of ACES buffer in an aqueous solution is 6.1 - 7.5.

Application

ACES has been used:

  • as a component of buffered charcoal yeast extract (BYCE) agar for plating bacteria culture and Buffered Yeast Extract (BYE) liquid medium to culture bacteria
  • to study the impact of the pH shift on the thermal inactivation of bacterial (Bacillus subtills) spores
  • as a buffer system to study the depolymerization of starch by α-amylase during exposure to hydrostatic pressure.
It is also suitable for use: as buffers for both agarose and polyacrylamide gel electrophoresis; in the isoelectric focusing of proteins; in the analysis of bacterial autolysins in a discontinuous sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) system.

Other Notes

The product is intended for laboratory use only, and it is not suitable for drug, household, or other purposes.


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Global Trade Item Number

SKUGTIN
A9758-25G04061833412336
A9758-100G04061835265152
A9758-1KG04061835265169
A9758-250G04061835265176