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A9758

ACES

≥99.0% (titration)

Synonym(s):

2-[(2-Amino-2-oxoethyl)azaniumyl]ethanesulfonate, 2-[(Carbamoylmethyl)amino]ethane-1-sulfonic acid, N-(2-Acetamido)-2-aminoethanesulfonic acid, N-(Carbamoylmethyl)-2-aminoethanesulfonic acid, N-(Carbamoylmethyl)taurine

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About This Item

Linear Formula:
H2NCOCH2NHCH2CH2SO3H
CAS Number:
7365-82-4
Molecular Weight:
182.20
UNSPSC Code:
12161700
NACRES:
NA.25
PubChem Substance ID:
24891495
EC Number:
230-908-4
Beilstein/REAXYS Number:
2253770
MDL number:
MFCD00008030
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Quality Level

200

assay

≥99.0% (titration)

form

crystalline powder

pH

3.0-4.5

useful pH range

6.1-7.5

pKa (25 °C)

6.8

mp

>220 °C (dec.) (lit.)

solubility

water: 0.523 g/mL, clear, colorless

application(s)

diagnostic assay manufacturing

storage temp.

room temp

SMILES string

NC(=O)CNCCS(O)(=O)=O

InChI

1S/C4H10N2O4S/c5-4(7)3-6-1-2-11(8,9)10/h6H,1-3H2,(H2,5,7)(H,8,9,10)

InChI key

DBXNUXBLKRLWFA-UHFFFAOYSA-N

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General description

N-(2-Acetamido)-2-aminoethanesulfonic acid (ACES) is a zwitterionic buffer used in biochemistry and molecular biology research. It is one of the Good′s buffers with a pH range of 6.15 - 8.35. The preferred range of ACES buffer in an aqueous solution is 6.1 - 7.5.

Application

ACES has been used:

  • as a component of buffered charcoal yeast extract (BYCE) agar for plating bacteria culture and Buffered Yeast Extract (BYE) liquid medium to culture bacteria
  • to study the impact of the pH shift on the thermal inactivation of bacterial (Bacillus subtills) spores
  • as a buffer system to study the depolymerization of starch by α-amylase during exposure to hydrostatic pressure.
It is also suitable for use: as buffers for both agarose and polyacrylamide gel electrophoresis; in the isoelectric focusing of proteins; in the analysis of bacterial autolysins in a discontinuous sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE) system.

Other Notes

The product is intended for laboratory use only, and it is not suitable for drug, household, or other purposes.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000546526
0000538019
0000536888
0000539179
0000532753

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Catalytic activity of $\beta$-amylase from barley in different pressure/temperature domains
Heinz V, et al.
Biotechnology Progress (2005)
Shift of pH-value during thermal treatments in buffer solutions and selected foods
Reineke K, et al.
International journal of food properties (2011)
High-content assay to measure mitochondrial function and bacterial vacuole size in infected human primary macrophages
Drame M, et al.
STAR protocols (2023)
Shadi Asadollahi et al.
International clinical psychopharmacology, 30(3), 142-150 (2014-12-17)
The objective of this study was to compare the efficacy of valproate versus haloperidol in decreasing the agitation level in affected patients in the emergency department. We assigned 80 acutely agitated patients to receive either intravenous sodium valproate (20 mg/kg)
COMET challenges paradigm of ACE inhibition in mild heart failure.
Cardiovascular journal of South Africa : official journal for Southern Africa Cardiac Society [and] South African Society of Cardiac Practitioners, 14(4), 207-208 (2003-11-19)
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Product Information Sheet - A9758

Product Information Sheet

Global Trade Item Number

SKUGTIN
A9758-25G04061833412336
A9758-250G04061835265176
A9758-1KG04061835265169
A9758-100G04061835265152

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