AV39137
Anti-TSC22D2 (AB1) antibody produced in rabbit
affinity isolated antibody
Synonym(s):
Anti-TSC22 domain family, member 2
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
79 kDa
species reactivity
guinea pig, human, mouse, dog, rat, rabbit, bovine
concentration
0.5 mg - 1 mg/mL
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TSC22D2(9819)
Immunogen
Synthetic peptide directed towards the N terminal region of human TSC22D2
Biochem/physiol Actions
Transforming growth factor (TGF)-β-stimulated clone 22 domain family of leucine zippers is involved in cellular osmotic stress response. TSC22D isoforms are regulated by glucocorticoids and TGF-β and aid the renal cells to adapt to hypertonicity.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: CFQITSVTTAQVATSITEDTESLDDPDESRTEDVSSEIFDVSRATDYGPE
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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Fang Liang et al.
International journal of oncology, 49(3), 1046-1056 (2016-08-31)
We previously identified TSC22D2 (transforming growth factor β-stimulated clone 22 domain family, member 2) as a novel cancer-associated gene in a rare multi-cancer family. However, its role in tumor development remains completely unknown. In this study, we found that TSC22D2 was
Diego F Fiol et al.
The FEBS journal, 274(1), 109-124 (2006-12-07)
We recently cloned a novel osmotic stress transcription factor 1 (OSTF1) from gills of euryhaline tilapia (Oreochromis mossambicus) and demonstrated that acute hyperosmotic stress transiently increases OSTF1 mRNA and protein abundance [Fiol DF, Kültz D (2005) Proc Natl Acad Sci
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