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Merck
CN

AV44851

Anti-PARL antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-PRO2207, Anti-PSARL, Anti-PSARL1, Anti-PSENIP2, Anti-Presenilin associated, rhomboid-like, Anti-RHBDS1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

36 kDa

species reactivity

mouse, rabbit, horse, pig, human, rat, dog

concentration

0.5 mg - 1 mg/mL

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_061092

UniProt accession no.

Q9H300-2

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... PARL(55486)

Related Categories

Immunogen

Synthetic peptide directed towards the N terminal region of human PARL

Application

Anti-PARL antibody produced in rabbit is suitable for western blotting at a concentration of 0.5μg/ml and for immunohistochemistry of paraffin-embedded tissue sections at a concentration of 4-8μg/ml.

Biochem/physiol Actions

Presenilin-associated rhomboid-like (PARL) is a mitochondrial rhomboid serine protease reported to mediate the cleavage of PINK1, a mitochondrial Ser/Thr protein kinase.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: SLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQSYFDGIKADWLDSIRPQ

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
QC14615

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Shiori Sekine et al.
The Journal of biological chemistry, 287(41), 34635-34645 (2012-08-24)
Regulated intramembrane proteolysis is a widely conserved mechanism for controlling diverse biological processes. Considering that proteolysis is irreversible, it must be precisely regulated in a context-dependent manner. Here, we show that phosphoglycerate mutase 5 (PGAM5), a mitochondrial Ser/Thr protein phosphatase

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