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Merck
CN

AV51100

Sigma-Aldrich

Anti-MSL3L2 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-Male-specific lethal 3-like 2 (Drosophila)

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

Key Documents

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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

51 kDa

species reactivity

human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

XP_001715283

UniProt accession no.

P0C860

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... MSL3L2(151507)

Immunogen

Synthetic peptide directed towards the middle region of human MSL3L2

Application

Anti-MSL3L2 antibody produced in rabbit is suitable for western blotting at a concentration of 1.0μg/ml.

Biochem/physiol Actions

Male-specific lethal 3 homolog (Drosophila) pseudogene 1 (MSL3P1; MSL3L2) forms a multisubunit human histone acetyltransferase complex (hMSL) that is involved in H4 acetylation at lysine 16. Acetylationof H4 is represses the expression of some genes and cell cycle arrest in G2/M phase.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: EKLSPSLRLLNPSRPQSTESQSTSGEPATPKRRKAEPQAVQSLRRSSPHT

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品

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Certificates of Analysis (COA)

Lot/Batch Number
QC22739

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Edwin R Smith et al.
Molecular and cellular biology, 25(21), 9175-9188 (2005-10-18)
We describe a stable, multisubunit human histone acetyltransferase complex (hMSL) that contains homologs of the Drosophila dosage compensation proteins MOF, MSL1, MSL2, and MSL3. This complex shows strong specificity for histone H4 lysine 16 in chromatin in vitro, and RNA

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