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B5934

Barbital Buffer

Name: Barbital Buffer
Brand: SIGMA

Synonym(s):

Barbital buffer solution, Sodium barbital buffer solution

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About This Item

UNSPSC Code:

12161703

NACRES:

NA.32

MDL number:

MFCD00130602

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description

When reconstituted to 1 liter each vial produces a 1× running buffer containing 60 mM sodium barbital, pH 8.6.

Quality Level

100

form

powder

drug control

Home Office Schedule 3; psychotrope (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IV (Portugal); Pszichotróp anyag / Psychotropic Substance (Hungary), 78/2022. (XII. 28.) BM rendelet, kontrollierte Droge in Deutschland

Related Categories

Biochemicals

Biological Buffers

Chemistry & Biochemicals

Application

Barbital buffer has been used:

to cast 1% agarose gels and to run agarose gel electrophoresis
to perform electrophoresis for lipoprotein-X (Lp-X) and lipoprotein separation
to perform electrophoresis for lipoprotein analysis

Biochem/physiol Actions

The most commonly used buffer for immunoelectrophoresis or immunodiffusion of protein on agarose gels or cellulose acetate. It is also used for separation of serum proteins, lipoproteins and isoenzymes.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302,H315,H319,H335,H361d,H371

pcodes

P201 - P202 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P311

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT SE 2 - STOT SE 3

target_organs

Nervous system, Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number

0000522609

0000471335

0000468009

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LCAT protects against Lipoprotein-X formation in a murine model of drug-induced intrahepatic cholestasis.

Marcelo J A Amar et al.

Pharmacology research & perspectives, 8(1), e00554-e00554 (2020-01-02)

Familial lecithin:cholesterol acyltransferase (LCAT) deficiency (FLD) is a rare genetic disease characterized by low HDL-C levels, low plasma cholesterol esterification, and the formation of Lipoprotein-X (Lp-X), an abnormal cholesterol-rich lipoprotein particle. LCAT deficiency causes corneal opacities, normochromic normocytic anemia, and

Impact of serum amyloid A on high density lipoprotein composition and levels.

Maria C de Beer et al.

Journal of lipid research, 51(11), 3117-3125 (2010-07-30)

Serum amyloid A (SAA) is an acute-phase protein mainly associated with HDL. To study the role of SAA in mediating changes in HDL composition and metabolism during inflammation, we generated mice in which the two major acute-phase SAA isoforms, SAA1.1

LCAT deficiency does not impair amyloid metabolism in APP/PS1 mice.

Sophie Stukas et al.

Journal of lipid research, 55(8), 1721-1729 (2014-06-22)

A key step in plasma HDL maturation from discoidal to spherical particles is the esterification of cholesterol to cholesteryl ester, which is catalyzed by LCAT. HDL-like lipoproteins in cerebrospinal fluid (CSF) are also spherical, whereas nascent lipoprotein particles secreted from

Global Trade Item Number

SKU	GTIN
B5934-12VL	04061833434307
B5934-1VL	04061832842493

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