B8684
Bambuterol hydrochloride
>98% (HPLC), β-adrenoceptor agonist, powder
Synonym(s):
Dimethylcarbmic acid 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester
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About This Item
Linear Formula:
C18H29N3O5 · HCl
CAS Number:
Molecular Weight:
403.90
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
>98% (HPLC)
Form:
powder
Storage condition:
desiccated
Product Name
Bambuterol hydrochloride, >98% (HPLC), powder
Quality Segment
assay
>98% (HPLC)
form
powder
storage condition
desiccated
color
off-white
solubility
H2O: soluble ~33 mg/mL
originator
AstraZeneca
SMILES string
Cl.CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C
InChI
1S/C18H29N3O5.ClH/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7;/h8-10,15,19,22H,11H2,1-7H3;1H
InChI key
LBARATORRVNNQM-UHFFFAOYSA-N
General description
Bambuterol is present in various tissues, like , intestine, lungs, liver and heart. It is also found in serum.
Application
Bambuterol hydrochloride has been used as a β2-adrenergic receptor (β2-AR) agonist to study its effects on graft versus host disease (GVHD) while preserving the graft-versus-tumor (GvT) effect. It has also been used in the preparation of bambuterol-poly vinyl chloride (Bb-PVC) membrane sensors for the determination of bambuterol in the pharmaceutical dosage form.
Biochem/physiol Actions
Bambuterol hydrochloride is used for prophylaxis and also to treat chronic bronchitis and chronic asthma in pediatrics.
β-adrenoceptor agonist; bronchodilator; anti-asthmatic; terbutaline prodrug
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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