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B8684

Bambuterol hydrochloride

Name: Bambuterol hydrochloride
Brand: SIGMA

>98% (HPLC), β-adrenoceptor agonist, powder

Synonym(s):

Dimethylcarbmic acid 5-[2-[(1,1-dimethylethyl)amino]-1-hydroxyethyl]-1,3-phenylene ester

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About This Item

Linear Formula:

C₁₈H₂₉N₃O₅ · HCl

CAS Number:

81732-46-9

Molecular Weight:

403.90

UNSPSC Code:

12352200

PubChem Substance ID:

329773137

NACRES:

NA.77

MDL number:

MFCD03427293

Assay:

>98% (HPLC)

Form:

powder

Storage condition:

desiccated

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Properties

Product Name

Bambuterol hydrochloride, >98% (HPLC), powder

Quality Segment

100

assay

>98% (HPLC)

form

powder

storage condition

desiccated

color

off-white

solubility

H₂O: soluble ~33 mg/mL

originator

AstraZeneca

SMILES string

Cl.CN(C)C(=O)Oc1cc(OC(=O)N(C)C)cc(c1)C(O)CNC(C)(C)C

InChI

1S/C18H29N3O5.ClH/c1-18(2,3)19-11-15(22)12-8-13(25-16(23)20(4)5)10-14(9-12)26-17(24)21(6)7;/h8-10,15,19,22H,11H2,1-7H3;1H

InChI key

LBARATORRVNNQM-UHFFFAOYSA-N

Description

General description

Bambuterol is present in various tissues, like , intestine, lungs, liver and heart. It is also found in serum.

Application

Bambuterol hydrochloride has been used as a β2-adrenergic receptor (β2-AR) agonist to study its effects on graft versus host disease (GVHD) while preserving the graft-versus-tumor (GvT) effect. It has also been used in the preparation of bambuterol-poly vinyl chloride (Bb-PVC) membrane sensors for the determination of bambuterol in the pharmaceutical dosage form.

Biochem/physiol Actions

Bambuterol hydrochloride is used for prophylaxis and also to treat chronic bronchitis and chronic asthma in pediatrics.

β-adrenoceptor agonist; bronchodilator; anti-asthmatic; terbutaline prodrug

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Articles

DISCOVER Bioactive Small Molecules for Neuroscience

Global Trade Item Number

SKU	GTIN
B8684-50MG	04061832079387
B8684-10MG	04061832088839