C1240
Chlormethiazole hydrochloride
≥98% (HPLC), GABAA agonist, powder
Synonym(s):
4-methyl-5-(β-chloroethyl)thiazole hydrochloride, 5-(2-Chloroethyl)-4-methylthiazole hydrochloride, Clomethiazole hydrochloride, Somnevrin hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C6H8ClNS · HCl
CAS Number:
Molecular Weight:
198.11
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Product Name
Chlormethiazole hydrochloride, ≥98% (HPLC), powder
description
Store desiccated
Quality Segment
assay
≥98% (HPLC)
form
powder
color
off-white
solubility
H2O: soluble >10 mg/mL
originator
AstraZeneca
SMILES string
Cl.Cc1ncsc1CCCl
InChI
1S/C6H8ClNS.ClH/c1-5-6(2-3-7)9-4-8-5;/h4H,2-3H2,1H3;1H
InChI key
OFXYKSLKNMTBHK-UHFFFAOYSA-N
Biochem/physiol Actions
Chlormethiazole serves as an anticonvulsant. It is useful in treating alcohol addiction and eclampsia. Chlormethiazole is also useful in treating convulsive status epilepticus. Long term administration of chlormethiazole leads to addiction to the drug.
GABAA agonist; glycine receptor modulator.
Features and Benefits
This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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