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Merck
CN

C5929

Calcium carbonate

BioReagent, suitable for insect cell culture, ≥99.0%

Synonym(s):

Limestone, calcite, calofort u, chalk, marble

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About This Item

Linear Formula:
CaCO3
CAS Number:
471-34-1
Molecular Weight:
100.09
UNSPSC Code:
12352207
NACRES:
NA.71
PubChem Substance ID:
24892821
EC Number:
207-439-9
Beilstein/REAXYS Number:
8008338
MDL number:
MFCD00010906

Key Documents

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Product Name

Calcium carbonate, BioReagent, suitable for insect cell culture, ≥99.0%

InChI key

VTYYLEPIZMXCLO-UHFFFAOYSA-L

InChI

1S/CH2O3.Ca/c2-1(3)4;/h(H2,2,3,4);/q;+2/p-2

SMILES string

[Ca++].[O-]C([O-])=O

product line

BioReagent

assay

≥99.0%

form

powder

technique(s)

cell culture | insect: suitable

solubility

H2O: soluble (10 g + 20 mL of HCl, dilute to 150 mL with H2O)

density

2.93 g/mL at 25 °C (lit.)

Quality Level

200

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Application

Calcium carbonate buffer has been used as a component of alginate solution for tissue culture, and for preparing conductive alginate-coated electrodes. It has also been used in the preparation of alginate hydrogel for drug delivery.

Biochem/physiol Actions

Calcium carbonate aids in bone formation and mineralization. It is often used as an antacid due to its potent alkalizing properties. Calcium carbonate has good biocompatibility, porous structure, large surface area, and high loading capacity. These properties of calcium carbonate make it favorable to use as a drug delivery system. In addition, the lower solubility of calcium carbonate (CaCO3) makes it effective in reducing the gelation rate and prolonging the working time for alginate gels. Therefore, it is widely used in the preparation of alginate solution.

Features and Benefits

  • BioReagent grade.
  • High level of assay ( ≥99.0%), indicating its purity.
  • Designed for insect cell culture applications.

General description

Calcium carbonate (CaCO3) is a ternary ionic compound formed by carbon, oxygen, and calcium. It is one of the most common minerals found in rocks worldwide. It aids in studying the process of biomineralization, where it participates in the formation of various mineral structures including marine sediments, shells of marine organisms, snails, coal balls, pearls, and eggshells. CaCO3 exists in different mineral forms such as calcite, aragonite, and vaterite.

Storage Class

13 - Non Combustible Solids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000508484
0000508484
0000467872
0000467872
0000444327

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Rapid Prototyping Method for 3D Printed Biomaterial Constructs with Vascular Structures
Gullo R M, et al.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, , 5729-5732 (2018)
Calcium carbonate formation and dissolution
Morse J W, et al.
Chemical Reviews, 107(2), 342-381 (2007)
Calcium Carbonate
Kristina Fritz
StatPearls [Internet] (2023)
Injectable polysaccharide hydrogel embedded with hydroxyapatite and calcium carbonate for drug delivery and bone tissue engineering
Ren B, et al.
International Journal of Biological Macromolecules, 118(Pt A), 1257-1266 (2018)
Calcium carbonate
Omari MMH, et al.
Analytical profiles of drug substances and excipients, 41 (2016)
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