biological source
human ovary
packaging
tube of 5 μg 07071909-DNA-5UG
pkg of vial of cells 07071909-1VL
growth mode
Adherent
karyotype
Modal chromosome no. 47 (46 - 47)
morphology
Polygonal & fusiform
products
Not specified
receptors
Not specified
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
cancer
shipped in
dry ice
storage temp.
−196°C
Application
COV434 has been used to study:
- the effect of 17β-estradiol on granulosa cell tumor growth, migration and invasion
- if mutant p53 (inactivatible R248Q hotspot mutation) works as a cancer-specific drug target
- the expression of TLR (toll-like receptor) and its function in the cell line
Biochem/physiol Actions
Human ovarian granulosa tumour
Human ovarian granulosa tumour cell line established from a solid primary tumour.
Preparation Note
DMEM + 2mM Glutamine + 10% Foetal Bovine Serum (FBS)
Split confluent cultures 1:2 to 1:5 i.e. seeding at 2-4x10,000 cells/cm2 using trypsin/EDTA; 5% CO2; 37°C.
Other Notes
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