DMS 92
NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA.
biological source
human lung (bone marrow metastasis)
packaging
tube of 5 μg 95062825-DNA-5UG
pkg of vial of cells 95062825-1VL
growth mode
Aggregates in suspension
karyotype
Modal no. 44
morphology
Not specified
products
Not specified
receptors
Not specified
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
metastasis
shipped in
dry ice
storage temp.
−196°C
Application
Human lung tumour model
Biochem/physiol Actions
DMS 92 was obtained from a bone marrow aspirate of an untreated 39 year old male at time of diagnosis. The isolated cells were identified as small cell carcinoma of the lung (SCLC). DMS 92 cells secrete adrenocorticotropin (ACTH), bombesin (BN), oxytocin-neurophysin (OT-NP) and 17 β-estradiol. Cells produce tumours in athymic nude mice.
Human Caucasian lung small cell carcinoma, metastasis to bone marrow
Preparation Note
Maintain cultures between 3-9x100,000 cells/ml; 5% CO2; 37°C.
Waymouth′s MB 752/1 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS) (Heat Inactivated).
Other Notes
Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.
Regulatory Information
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