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OE21 Cell Line human

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA, 96062201, human esophagus, Epithelial

Synonym(s):

JROECL 21 Cells, OE 21 Cells

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About This Item

UNSPSC Code:
41106514
Biological source:
human esophagus
Relevant disease(s):
cancer
Growth mode:
Adherent
Karyotype:
Aneuploid
Morphology:
Epithelial
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biological source

human esophagus

packaging

tube of 5 μg 96062201-DNA-5UG, pkg of vial of cells 96062201-1VL

growth mode

Adherent

karyotype

Aneuploid

morphology

Epithelial

products

Not specified

receptors

MHC class I

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

cancer

shipped in

dry ice

storage temp.

−196°C

Application

Study of oesophageal cancer

Biochem/physiol Actions

Human Caucasian oesophageal squamous cell carcinoma
OE21, also known as JROECL21, was established in 1993 from a squamous carcinoma of mid oesophagus of a 74 year-old male patient. The tumour was identified as pathological stage IIA(UICC) and showed moderate differentiation. HLA-A,-B and -C (MHC class I) are expressed constitutively, expression of ICAM-1 can be induced by treatment with interferon-gamma. OE21 cells express epithelial cytokeratins and are tumourigenic in nude mice.
STR-PCR Data: Amelogenin: X,Y
CSF1PO: 11,12
D13S317: 12
D16S539: 13
D5S818: 12,13
D7S820: 11,12
THO1: 8
TPOX: 8,11
vWA: 16,17

Preparation Note

RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).
Split sub-confluent cultures (70-80%) 1:8 i.e. seeding at 1x10,000 cells/cm2 using 0.25% trypsin or trypsin/EDTA; 5% CO2; 37°C.

Other Notes

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.

Regulatory Information

常规特殊物品
低风险生物材料
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