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Merck
CN

D6038

Supelco

Desoximetasone

Synonym(s):

9-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione

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About This Item

Empirical Formula (Hill Notation):
C22H29FO4
CAS Number:
382-67-2
Molecular Weight:
376.46
EC Number:
206-845-3
MDL number:
MFCD00083301
UNSPSC Code:
41116107
PubChem Substance ID:
24893994

Key Documents

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technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
veterinary

format

neat

SMILES string

[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C

InChI

1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1

InChI key

VWVSBHGCDBMOOT-IIEHVVJPSA-N

Gene Information

human ... NR3C1(2908)

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Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H302,H317,H361d

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2 - Skin Sens. 1

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
090M1300
096K1526
025K1047
101K1204
020K1603

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Parinbhai Shah et al.
Pharmaceutics, 12(3) (2020-03-19)
Topical corticosteroids are used to treat a variety of skin conditions such as allergic reactions, eczema, and psoriasis. Niosomes are a novel surfactant-based delivery system that may be used to deliver desoximetasone via topical product application in order to mitigate
Morbilliform erythema-multiforme-like eruption from desoxymethasone.
L Stingeni et al.
Contact dermatitis, 35(6), 363-364 (1996-12-01)
Premjit Juntongjin et al.
Dermatologic therapy, 32(4), e12956-e12956 (2019-05-10)
Topical potent corticosteroids are the mainstay of treatment for chronic hand eczema (CHE). However, there are numerous adverse effects associated with the chronic use of topical corticosteroids. Calcipotriol has been widely used in psoriasis and has been reported to achieve
S Teelucksingh et al.
The West Indian medical journal, 42(2), 77-78 (1993-06-01)
A case of Cushing's syndrome is described in a woman who self-treated psoriasis with a variety of potent topical glucocorticoids over 15 years. She was successfully weaned off corticosteroids and was treated with alternative anti-psoriatic drugs. The disappearance, nine months
Allergic reactions to topical desoxymethasone and oral triamcinolone.
L Brambilla et al.
Contact dermatitis, 21(4), 272-274 (1989-10-01)
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