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E4779

Anti-EphB4 antibody produced in goat

affinity isolated antibody, lyophilized powder

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About This Item

UNSPSC Code:
51111800
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
flow cytometry
immunohistochemistry
western blot
Species reactivity:
mouse
Citations:
3
Technique(s):
flow cytometry: suitable
immunohistochemistry: 5-15 μg/mL using cells and tissues
western blot: 0.1-0.2 μg/mL
Uniprot accession no.:
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Product Name

Anti-EphB4 antibody produced in goat, affinity isolated antibody, lyophilized powder

biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

species reactivity

mouse

technique(s)

flow cytometry: suitable
immunohistochemistry: 5-15 μg/mL using cells and tissues
western blot: 0.1-0.2 μg/mL

UniProt accession no.

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

mouse ... Ephb4(13846)

Related Categories

Biochem/physiol Actions

EPH receptor B4 is a protein-tyrosine kinase family that belongs to the ephrin receptor subfamily. EphB receptors and EphrinB ligands have a regulatory effect on endothelial cell function, angiogenesis, migration, cell growth and survival.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

purified recombinant mouse EphB4 extracellular domain expressed in mouse NSO cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Andreas Benn et al.
Biomolecules, 10(3) (2020-03-27)
Vascular development is an orchestrated process of vessel formation from pre-existing vessels via sprouting and intussusceptive angiogenesis as well as vascular remodeling to generate the mature vasculature. Bone morphogenetic protein (BMP) signaling via intracellular SMAD1 and SMAD5 effectors regulates sprouting
Ombretta Salvucci et al.
Advances in cancer research, 114, 21-57 (2012-05-17)
Eph receptor tyrosine kinases and their Ephrin ligands represent an important signaling system with widespread roles in cell physiology and disease. Receptors and ligands in this family are anchored to the cell surface; thus Eph/Ephrin interactions mainly occur at sites
eph, the largest known family of putative growth factor receptors.
N L Tuzi et al.
British journal of cancer, 69(3), 417-421 (1994-03-01)

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