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About This Item
Empirical Formula (Hill Notation):
C20H24O10
CAS Number:
Molecular Weight:
424.40
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:
Quality Level
assay
≥90% (HPLC)
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
food and beverages
format
neat
storage temp.
−20°C
SMILES string
C[C@@H]1C(=O)O[C@H]2[C@H](O)[C@@]34[C@H]5C[C@@H](C(C)(C)C)[C@@]36[C@@H](O)C(=O)O[C@H]6O[C@@]4(C(=O)O5)[C@@]12O
InChI
1S/C20H24O10/c1-6-12(23)28-11-9(21)18-8-5-7(16(2,3)4)17(18)10(22)13(24)29-15(17)30-20(18,14(25)27-8)19(6,11)26/h6-11,15,21-22,26H,5H2,1-4H3/t6-,7+,8-,9+,10+,11+,15+,17+,18+,19-,20-/m1/s1
InChI key
SQOJOAFXDQDRGF-MMQTXUMRSA-N
General description
Ginkgolide B from Ginkgo biloba leaves is a terpene lactone and one of the main molecular form of ginkgolides, present in Ginkgo biloba leaves. It is widely used to treat peripheral and cerebral circulation disorders.
Application
Ginkgolide B from Ginkgo biloba leaves is used as an analytical reference standard:
- For the chromatographic separation of the analyte in Ginkgo biloba leaves extract and to study the antimicrobial activity exerted on a variety of Gram-positive and -negative bacteria and yeasts.
- For the determination of the analyte in Ginkgo biloba L. phytopharmaceuticals using high-performance liquid chromatography technique.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Primary constituent of Ginkgo biloba. Potential anticancer agent and neuroprotective.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
监管及禁止进口产品
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Antimicrobial investigation of semi-purified fractions of Ginkgo biloba leaves
Mazzanti.G, et al.
Journal of Ethnopharmacology, 71(1-2), 83-88 (2005)
Christoph A Reichel et al.
PloS one, 6(2), e17229-e17229 (2011-03-03)
Clinical trials revealed beneficial effects of the broad-spectrum serine protease inhibitor aprotinin on the prevention of ischemia-reperfusion (I/R) injury. The underlying mechanisms remained largely unclear. Using in vivo microscopy on the cremaster muscle of male C57BL/6 mice, aprotinin as well
Yuan Yuan et al.
Journal of chromatographic science, 51(3), 266-272 (2012-08-31)
A sensitive, simple and rapid liquid chromatography-tandem mass spectrometry method was developed and validated for the simultaneous determination of ginkgolide B (GB) and the prodrug of ginkgolide B (PGB) in rat plasma and brain tissue. Detection was performed on a
Global Trade Item Number
| SKU | GTIN |
|---|---|
| G6910-10MG | 04061833642207 |
| G6910-50MG | 04061833284896 |
