Skip to Content
Merck
CN

H5136

Hydromorphone hydrochloride

Synonym(s):

(5α)-4,5-Epoxy-3-hydroxy-17-methyl-morphinan-6-one hydrochloride, Hydromorphone HCl

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C17H19NO3 · HCl
CAS Number:
71-68-1
Molecular Weight:
321.80
NACRES:
NA.77
PubChem Substance ID:
24895673
UNSPSC Code:
12352200
EC Number:
200-762-6
MDL number:
MFCD03427563

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C17H19NO3.ClH/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18;/h2,4,10-11,16,19H,3,5-8H2,1H3;1H/t10-,11+,16-,17-;/m0./s1

InChI key

XHILEZUETWRSHC-NRGUFEMZSA-N

SMILES string

OC1=C(O2)C3=C(C[C@@H]4[C@@]5([H])[C@@]3([C@]2([H])C(CC5)=O)CCN4C)C=C1.[H]Cl

drug control

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal), kontrollierte Droge in Deutschland

Quality Level

200

Gene Information

human ... OPRM1(4988)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

solubility

H2O: >10 mg/mL

application(s)

forensics and toxicology
veterinary

Looking for similar products? Visit Product Comparison Guide

Related Categories

Biochem/physiol Actions

Narcotic opiate analgesic; μ opioid receptor agonist.

Legal Information

German
Dieses Produkt fällt unter das Betäubungsmittelgesetz (BtMG). Für eine Bestellung dieses Produktes ist eine Erlaubnis nach § 3 BtMG zwingend erforderlich, es sei denn, es greift eine Ausnahme von der Erlaubnispflicht nach § 4 oder § 26 BtMG.

English
This product is subject to the German Narcotics Act. A permit under Section 3 of the German Narcotics Act is mandatory for ordering this product unless an exemption from the permit requirement under Section 4 or Section 26 of the German Narcotics Act applies.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302,H336

Hazard Classifications

Acute Tox. 4 Oral - STOT SE 3

target_organs

Central nervous system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0000487483
0000487514
0000487514
0000487483
0000464799

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

H M Korani et al.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T, 28(6), 409-416 (2015-10-10)
Evaluate variability associated with assessing changes in the position of uncemented femoral stems. Stem level, canal fill, stem angle, and version angle were measured on craniocaudal horizontal beam (CCHB) and open leg lateral (OLL) radiographic projections of the femur of
E M Costa et al.
Life sciences, 50(1), 73-81 (1992-01-01)
SH-SY5Y (human neuroblastoma) cultured cells, known to have mu-opioid receptors, have been used to assess and compare the ability of eight representative mu-selective compounds from diverse opioid families to recognize and activate these receptors. A wide range of receptor affinities
D L Cichewicz et al.
The Journal of pharmacology and experimental therapeutics, 289(2), 859-867 (1999-04-24)
The antinociceptive effects of various mu opioids given p.o. alone and in combination with Delta-9-tetrahydrocannabinol (Delta9-THC) were evaluated using the tail-flick test. Morphine preceded by Delta9-THC treatment (20 mg/kg) was significantly more potent than morphine alone, with an ED50 shift
P Sacerdote et al.
British journal of pharmacology, 121(4), 834-840 (1997-06-01)
1. Although it is well known that morphine induces significant immunosuppression, the potential immunosuppressive activity of morphine derived drugs commonly used in the treatment of pain (codeine, hydromorphone, oxycodone) has never been evaluated. 2. We evaluated in the mouse the

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service