H6903
HEPBS
≥99% (titration), powder, pH 7.6-9.0
Synonym(s):
PBS, phosphate buffered saline, N-(2-Hydroxyethyl)piperazine-N′-(4-butanesulfonic acid)
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About This Item
Empirical Formula (Hill Notation):
C10H22N2O4S
CAS Number:
Molecular Weight:
266.36
UNSPSC Code:
12161700
NACRES:
NA.25
MDL number:
Product Name
HEPBS, ≥99% (titration)
Quality Level
assay
≥99% (titration)
form
powder
pH
7.6-9.0
useful pH range
7.6-9.0
pKa (25 °C)
8.3
pKa
8.3
solubility
water: 0.5 g/mL, clear to slightly hazy, colorless to faintly yellow
application(s)
diagnostic assay manufacturing
SMILES string
[S](=O)(=O)(O)CCCCN1CCN(CC1)CCO
InChI
1S/C10H22N2O4S/c13-9-8-12-6-4-11(5-7-12)3-1-2-10-17(14,15)16/h13H,1-10H2,(H,14,15,16)
InChI key
LOJNFONOHINEFI-UHFFFAOYSA-N
General description
HEPBS/N-(2-Hydroxyethyl)piperazine-N′-(4-butanesulfonic acid) is mainly used in buffer preparations.
Other Notes
Homolog of HEPES and EPPS with higher pKa and similar utility in biological systems.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Template-Directed Synthesis in 3?-and 5?-Direction with Reversible Termination
Kaiser A, et al.
Angewandte Chemie (International Edition in English), 51(33), 8299-8303 (2012)
T Thiel et al.
Journal of biochemical and biophysical methods, 37(3), 117-129 (1998-12-31)
Four new zwitterionic butanesulfonic acid buffers that are structurally related to four families of Good buffers were evaluated for use in biological systems. These buffers, with pKa values from 7.6 to 10.7, were compared with a variety of other buffers
Michael Bachmann et al.
Journal of cell science, 133(9) (2020-03-21)
αVβ3 integrin can bind to multiple extracellular matrix proteins, including vitronectin (Vn) and fibronectin (Fn), which are often presented to cells in culture as homogenous substrates. However, in tissues, cells experience highly complex and changing environments. To better understand integrin
Global Trade Item Number
| SKU | GTIN |
|---|---|
| H6903-25G | 04061832548142 |
| H6903-100G | 04061833802588 |