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Merck
CN

H7375

Histamine bisphosphate monohydrate

Histamine receptor ligand

Synonym(s):

2-(4-Imidazolyl)ethylamine diphosphate salt, 2-(4-Imidazolyl)ethylamine diphosphate salt monohydrate, Histamine diphosphate salt monohydrate

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About This Item

Empirical Formula (Hill Notation):
C5H9N3 · 2H3PO4 · H2O
CAS Number:
Molecular Weight:
325.15
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
200-118-4
MDL number:
Beilstein/REAXYS Number:
3744619
Quality level:
Technical Service
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Product Name

Histamine bisphosphate monohydrate,

SMILES string

[H]O[H].OP(O)(O)=O.OP(O)(O)=O.NCCc1c[nH]cn1

InChI key

CNSGLKZGHLZDHQ-UHFFFAOYSA-N

InChI

1S/C5H9N3.2H3O4P.H2O/c6-2-1-5-3-7-4-8-5;2*1-5(2,3)4;/h3-4H,1-2,6H2,(H,7,8);2*(H3,1,2,3,4);1H2

storage temp.

−20°C

Quality Level

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signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Electroacupuncture at Fengchi(GB20) and Yanglingquan(GB34) Ameliorates Paralgesia through Microglia-Mediated Neuroinflammation in a Rat Model of Migraine.
Zhou, et al.
Brain sciences, 13 (2023)
I K Taylor et al.
Lancet (London, England), 337(8743), 690-694 (1991-03-23)
The effects of a highly selective leukotriene D4 receptor antagonist, ICI 204.219, on allergen-induced bronchoconstriction and changes in airway reactivity were evaluated in a double-blind, placebo-controlled, crossover trial. Ten atopic subjects were selected for the study on the basis of
A M Majchel et al.
The Journal of allergy and clinical immunology, 90(1), 85-91 (1992-07-01)
To evaluate changes in the nasal response to histamine, we challenged 19 subjects with allergic rhinitis caused by ragweed (RW) before, during, and after the RW season with increasing doses of histamine diphosphate. We compared their response, as measured by
R G van Wijk et al.
Allergy proceedings : the official journal of regional and state allergy societies, 14(4), 273-281 (1993-07-01)
For a study on the relationship between nasal hyperreactivity to histamine and the nasal response to allergen, 14 rhinitis patients allergic to house-dust mites were challenged with histamine and 5 days later with a house-dust mite (HDM) extract. According to
R A Kennis et al.
American journal of veterinary research, 59(1), 7-9 (1998-01-27)
To compare skin test reactivity of ID injected histamine phosphate in clinically normal dogs that were physically restrained or anesthetized with propofol. 12 clinically normal adult dogs. Nonanesthetized dogs (group 1) were restrained and shaved on the right side of

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