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J4252

Sigma-Aldrich

JWH-015

≥98% (HPLC), powder

Synonym(s):

(2-Methyl-1-propyl-1H-indol-3-yl)-1-naphthalenylmethanone

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About This Item

Empirical Formula (Hill Notation):
C23H21NO
CAS Number:
155471-08-2
Molecular Weight:
327.42
MDL number:
MFCD02094630
UNSPSC Code:
12352200
PubChem Substance ID:
24278502
NACRES:
NA.77

Quality Level

100

Assay

≥98% (HPLC)

form

powder

drug control

regulated under CDSA - not available from Sigma-Aldrich Canada

color

off-white

solubility

DMSO: >20 mg/mL (with heating)

storage temp.

−20°C

SMILES string

CCCn1c(C)c(C(=O)c2cccc3ccccc23)c4ccccc14

InChI

1S/C23H21NO/c1-3-15-24-16(2)22(20-12-6-7-14-21(20)24)23(25)19-13-8-10-17-9-4-5-11-18(17)19/h4-14H,3,15H2,1-2H3

InChI key

LJSBBBWQTLXQEN-UHFFFAOYSA-N

Application

JWH-015 has been used to study its effect on tumor-evoked pain behavior.[1] It has also been used to study its protective effects on rat brain mitochondria upon paraquat exposure.[2]

Biochem/physiol Actions

JWH-015 is a selective CB2 cannabinoid receptor agonist. JWH-015 is structurally classified as naphthoylindoles.[3]

Features and Benefits

This compound is featured on the Cannabinoid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
041M4613V
109K47062
109K47061
109K4706
018K4712

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