L4420
LY-367385 hydrochloride
≥98% (HPLC)
Synonym(s):
(S)-(+)-a-amino-4-carboxy-2-methylbenzeneacetic acid
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About This Item
Empirical Formula (Hill Notation):
C10H11NO4 ·HCl
CAS Number:
Molecular Weight:
245.66
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to off-white
solubility
H2O: >10 mg/mL
originator
Eli Lilly
storage temp.
room temp
SMILES string
Cc1cc(ccc1[C@H](N)C(O)=O)C(O)=O
InChI
1S/C10H11NO4/c1-5-4-6(9(12)13)2-3-7(5)8(11)10(14)15/h2-4,8H,11H2,1H3,(H,12,13)(H,14,15)/t8-/m0/s1
InChI key
SGIKDIUCJAUSRD-QMMMGPOBSA-N
Application
LY-367385 hydrochloride has been used as a non-N-methyl-D-aspartate (NMDA) glutamate receptor blocker in neuronal stimulation experiment.
Biochem/physiol Actions
LY-367385 hydrochloride has an ability to inhibit induction of long-term potentiation (LTP).
LY-367385 is a selective metabotropic glutamate 1a receptor (mGlu1a) antagonist.
Features and Benefits
This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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