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Merck
CN

M3199

Sigma-Aldrich

MK-212 hydrochloride

≥98% (HPLC)

Synonym(s):

2-Chloro-6-(1-piperazinyl)-pyrazine hydrochloride, 6-Chloro-2-(1-piperazinyl)pyrazine hydrochloride, NSC 31732

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About This Item

Empirical Formula (Hill Notation):
C8H11ClN4·HCl
CAS Number:
61655-58-1
Molecular Weight:
235.11
EC Number:
262-883-0
MDL number:
MFCD00673963
UNSPSC Code:
12352200
PubChem Substance ID:
329817966
NACRES:
NA.77

Key Documents

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Quality Level

100

Assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

white to off-white

solubility

DMSO: ≥20 mg/mL

storage temp.

2-8°C

SMILES string

Cl.Clc1cncc(n1)N2CCNCC2

InChI

1S/C8H11ClN4.ClH/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13;/h5-6,10H,1-4H2;1H

InChI key

PFIZGLUIYAZQFU-UHFFFAOYSA-N

Related Categories

Biochem/physiol Actions

Selective 5-HT2C serotonin receptor agonist.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
080M4602

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M L Pierce et al.
Neuroscience, 170(3), 827-838 (2010-07-24)
Neuronal networks generating rhythmic activity as an emergent property are common throughout the nervous system. Some are responsible for rhythmic behaviours, as is the case for the spinal cord locomotor networks; however, for others the function is more subtle and
Adriane M dela Cruz et al.
Behavioural pharmacology, 20(8), 720-730 (2009-11-11)
Only a subgroup of human drug users progress from initial drug taking to drug addiction. The learned associations between the effects of the drug and the environment in which it is experienced is an important aspect of the progression to
Martilias Farrell et al.
Psychopharmacology, 211(2), 149-159 (2010-06-08)
The extended ternary complex theory of receptor function states a ligand can be classified as an inverse agonist, agonist, or neutral antagonist based on its ability to preferentially stabilize the inactive conformation, the active conformation, or to have no preference
Janet L Neisewander et al.
Behavioural pharmacology, 18(8), 791-800 (2007-11-09)
The extinction/reinstatement model has been used in this study to examine the role of 5-HT2C receptors in cocaine-seeking behavior elicited by cocaine-associated cues and cocaine-priming injections. Rats that had been trained to press a lever for cocaine (0.75 mg/kg/0.1 ml
Kunihiro Nakai et al.
European journal of pain (London, England), 14(10), 999-1006 (2010-05-22)
Peripheral branches of the trigeminal nerve may be damaged during maxillofacial injury or surgical procedures and trigeminal trauma may induce severe pain that is very challenging to treat. Chronic constriction injury to the infraorbital nerve (ION-CCI) by loose ligatures has
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