Key Documents

View All Documentation

M8693

Melanotan II acetate salt

Name: Melanotan II acetate salt
Brand: SIGMA

≥95% (HPLC), MC3-R/MC4-R melanocortin agonist, lyophilized solid

Synonym(s):

Ac-[Nle⁴Asp⁵D-Phe⁷Lys¹⁰]α-MSH-(4-10)-NH₂

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₅₀H₆₉N₁₅O₉ · xC₂H₄O₂

CAS Number:

121062-08-6

Molecular Weight:

1024.18 (free base basis)

UNSPSC Code:

51111800

NACRES:

NA.32

MDL number:

MFCD06795842

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Melanotan II acetate salt, ≥95% (HPLC)

Quality Segment

200

assay

≥95% (HPLC)

form

lyophilized solid

color

white

solubility

H₂O: soluble 5 mg/mL

shipped in

dry ice

storage temp.

−20°C

SMILES string

[nH]1cncc1C[C@@H]2NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC2=O)Cc5ccccc5)CCCN=C(N)N)Cc3c4c([nH]c3)cccc4)C(=O)N)NC(=O)[C@@H](NC(=O)C)CCCC

InChI

1S/C50H69N15O9/c1-3-4-16-36(59-29(2)66)44(69)65-41-25-42(67)55-20-11-10-18-35(43(51)68)60-47(72)39(23-31-26-57-34-17-9-8-15-33(31)34)63-45(70)37(19-12-21-56-50(52)53)61-46(71)38(22-30-13-6-5-7-14-30)62-48(73)40(64-49(41)74)24-32-27-54-28-58-32/h5-9,13-15,17,26-28,35-41,57H,3-4,10-12,16,18-25H2,1-2H3,(H2,51,68)(H,54,58)(H,55,67)(H,59,66)(H,60,72)(H,61,71)(H,62,73)(H,63,70)(H,64,74)(H,65,69)(H4,52,53,56)/t35-,36-,37-,38+,39-,40-,41-/m0/s1

InChI key

JDKLPDJLXHXHNV-MFVUMRCOSA-N

Gene Information

human ... MC3R(4159), MC4R(4160)
mouse ... MC3R(17201), MC4R(17202)
rat ... MC3R(29310), MC4R(25635)

Description

General description

Melanotan II induces melanogenesis and thus increases skin pigmentation. It is an analog of α-melanocyte stimulating hormone.

Application

Melanotan II acetate salt has been used to study its inhibitory effects on feeding and energy expenditure in rats.

Biochem/physiol Actions

Melanotan II is a MC3-R/MC4-R melanocortin agonist.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c