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Merck
CN

MAK571

Sigma-Aldrich

ALT Activity Assay Kit

sufficient for 100 colorimetric or fluorometric tests

Synonym(s):

Alanine Aminotransferase Assay Kit, SGPT Activity Assay Kit

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About This Item

UNSPSC Code:
41116104
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usage

sufficient for 100 colorimetric or fluorometric tests

Quality Level

detection method

colorimetric
fluorometric

relevant disease(s)

drug-induced liver injury; non-alcoholic/simple fatty liver (NAFL); cancer

storage temp.

−20°C

General description

Alanine Aminotransferase (ALT), also known as serum glutamic-pyruvic transaminase (SGPT), is a pyridoxal-phosphate-dependent enzyme that facilitates the reversible transfer of an amino group from alanine to α-ketoglutarate, producing pyruvate and glutamate. Predominantly located in the liver and serum, ALT is also present in other tissues such as the heart and muscles. Its primary role in metabolism involves the gluconeogenesis pathway, where it helps convert amino acids into glucose precursors, thus playing a crucial part in energy production during fasting or intense exercise. Elevated serum ALT levels are indicative of hepatocellular injury and are commonly used as a biomarker for liver damage.

Application

Suitable for the measurement of alanine aminotransferase (ALT) activity in biological samples including tissue, cells, and serum.

Features and Benefits

Compatibility with High-Throughput Systems: Seamlessly integrate our kit into high-throughput handling systems, ensuring smooth operations and accurate results, enhancing efficiency in your laboratory workflow.


Convenient Data Analysis: Supportive calculator will calculate the reagents needed according to your experimental needs, and analyze your results based on your experimental data.


Click here to download a calculator excel file.

Pictograms

Health hazardCorrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Dam. 1 - Resp. Sens. 1 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Regulatory Information

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