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ML0014

Sigma-Aldrich

Alanine Metabolite Library

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storage temp.

−20°C

Quality Level

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General description

Alanine metabolism known also as Glucose-Alanine cycle or Cahill cycle is the process in which muscles utilize amino acids for their energetic needs.
  • Glutamate and Pyruvate are transformed into Alanine and α-ketoglutarate in the muscle, through the actions of Alanine aminotransferase (AST) and Pyridoxal Phosphate.
  • The α-ketoglutarate transforms to Glutamate through the actions of glutamate dehydrogenase with an addition of ammonia. But, in this pathway, the ammonia is excluded from the muscles.
  • The Alanine passes through the blood stream and into the liver. In the liver, the Alanine and a-ketoglutarate transform to Pyruvate and Glutamate by the actions of Alanine aminotransferase (AST).
  • The Pyruvate transforms to glucose by the Cori cycle (Gluconeogenesis) and returns to the muscle from the blood stream.

Packaging

Components:

Each vial is packaged individually and contains 10 mg of the Alanine pathway metabolite standards.

Kit Components Also Available Separately

Product No.
Description
SDS

  • A2754Adenosine 5′-diphosphate sodium salt, bacterial, ≥95% (HPLC) 10 mgSDS

  • A2252Adenosine 5′-monophosphate monohydrate, from yeast, ≥97% 10 mgSDS

  • A2383Adenosine 5′-triphosphate disodium salt hydrate, Grade I, ≥99%, from microbial 10 mgSDS

  • B4501Biotin, ≥99% (HPLC), lyophilized powder 10 mgSDS

  • G7126Glycine, ReagentPlus®, ≥99% (HPLC) 10 mgSDS

  • G10601Glyoxylic acid monohydrate, 98% 10 mgSDS

  • A7627L-Alanine, ≥98% (TLC) 10 mgSDS

  • L-Glutamic acid 10 mg

  • O4126Oxaloacetic acid, ≥97% (HPLC) 10 mgSDS

  • K1750α-Ketoglutaric acid, ≥98.5% (NaOH, titration) 10 mgSDS

  • P9255Pyridoxal 5′-phosphate hydrate, ≥98% 10 mgSDS

  • P8010Sodium pyrophosphate tetrabasic, ≥95% 10 mgSDS

  • Sodium pyruvate 10 mg

See All (13)

Pictograms

CorrosionExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Oral - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3


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