N1415
Naratriptan hydrochloride
≥98% (HPLC)
Synonym(s):
Amerge, GR-85548A, N-Methyl-3-(1-methyl-4-piperidinyl)-1H-indole-5-ethanesulfonamide hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C17H25N3O2S ·HCl
CAS Number:
Molecular Weight:
371.93
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
H2O: ≥10 mg/mL
originator
GlaxoSmithKline
storage temp.
room temp
SMILES string
Cl.CNS(=O)(=O)CCc1ccc2[nH]cc(C3CCN(C)CC3)c2c1
InChI
1S/C17H25N3O2S.ClH/c1-18-23(21,22)10-7-13-3-4-17-15(11-13)16(12-19-17)14-5-8-20(2)9-6-14;/h3-4,11-12,14,18-19H,5-10H2,1-2H3;1H
InChI key
AWEZYKMQFAUBTD-UHFFFAOYSA-N
Gene Information
human ... HTR1B(3351), HTR1D(3352)
Biochem/physiol Actions
Naratriptan hydrochloride is a triptan drug that is used to relieve acute migraine headaches. It has poor bioavailability, short half-life, and the incidence of migraine recurrence therefore, it is occasionally used.
Naratriptan hydrochloride is a serotonin 5-HT1B/1D receptor agonist.
Features and Benefits
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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