N3288
(+)-Norfenfluramine hydrochloride
≥98% (HPLC), 5-HT2A/2B agonist, powder
Synonym(s):
JP 92, NSC 43036, S-(+)-α-Methyl-3-(trifluoromethyl)benzeneethanamine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C10H12F3N · HCl
CAS Number:
Molecular Weight:
239.67
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Product Name
(+)-Norfenfluramine hydrochloride, ≥98% (HPLC), powder
Quality Segment
assay
≥98% (HPLC)
form
powder
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
storage condition
desiccated
color
white
solubility
H2O: >10 mg/mL
storage temp.
2-8°C
SMILES string
Cl.C[C@H](N)Cc1cccc(c1)C(F)(F)F
InChI
1S/C10H12F3N.ClH/c1-7(14)5-8-3-2-4-9(6-8)10(11,12)13;/h2-4,6-7H,5,14H2,1H3;1H/t7-;/m0./s1
InChI key
PIDLOFBRTWNFAR-FJXQXJEOSA-N
Biochem/physiol Actions
(+)-Norfenfluramine is the major hepatic metabolite of (+)-fenfluramine and is primarily responsible for the anorexic effect, as well as side effects; (+)-norfenfluramine causes vasoconstriction and a blood pressure increase in rats with normal blood; acts primarily on the cytoplasmic pool of serotonin; more potent than fenfluramine at inducing dopamine release.
Potent substrate for serotonin transporter; 5-HT2A/2B agonist; anorectic
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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