O3007
Ochratoxin A−BSA conjugate from Aspergillus ochraceus
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About This Item
CAS Number:
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
extent of labeling
3-6 mol ochratoxin A per mol BSA
Quality Segment
storage temp.
2-8°C
SMILES string
O=C1O[C@H](C)CC2=C(Cl)C=C(C(N[C@H](C(O)=O)CC3=CC=CC=C3)=O)C(O)=C21
InChI
1S/C20H18ClNO6/c1-10-7-12-14(21)9-13(17(23)16(12)20(27)28-10)18(24)22-15(19(25)26)8-11-5-3-2-4-6-11/h2-6,9-10,15,23H,7-8H2,1H3,(H,22,24)(H,25,26)/t10-,15+/m1/s1
InChI key
RWQKHEORZBHNRI-BMIGLBTASA-N
Application
Ochratoxin A−BSA conjugate from Aspergillus ochraceus has been used in carbonate-bicarbonate buffer to coat the high-affinity 96-well polystyrene plates for indirect competitive enzyme-linked immunosorbent assay. It has also been used as a standard in the determination of ochratoxin A in serum by capillary electrophoresis with laser-induced fluorescence detection (CE-LIF).
Biochem/physiol Actions
Ochratoxin A (OTA) is a mycotoxin that is the most toxic among the other ochratoxins. It is produced by Aspergillus carbonarius, A. ochraceus, and Penicillium verrucosum. OTA acts as a major food contaminant and is considered nephrotoxic, teratogenic, neurotoxic, hepatotoxic, and immunotoxic. OTA is known to elevate oxidative stress at a cellular level.
signalword
Danger
Hazard Classifications
Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Carc. 1B - Repr. 1B
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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