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Merck
CN

P1504

TWEEN® 40

viscous liquid

Synonym(s):

Polyoxyethylenesorbitan monopalmitate

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About This Item

CAS Number:
9005-66-7
UNSPSC Code:
12161900
NACRES:
NA.25
MDL number:
MFCD00165345

Key Documents

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SMILES string

O1C(C(C(C1)OCCO)OCCO)C(OCCO)COCCOC(=O)CCCCCCCCCCC

InChI

1S/C26H50O10/c1-2-3-4-5-6-7-8-9-10-11-24(30)34-19-18-31-20-22(32-15-12-27)26-25(35-17-14-29)23(21-36-26)33-16-13-28/h22-23,25-29H,2-21H2,1H3

InChI key

HMFKFHLTUCJZJO-UHFFFAOYSA-N

description

non-ionic

assay

~90.0% (GC)

form

viscous liquid

mol wt

estimated mol wt 1277

composition

Palmitic acid, ~90% (balance primarily stearic acid)

technique(s)

DNA extraction: suitable, RNA extraction: suitable, cell culture | mammalian: suitable, protein purification: suitable

CMC

0.027 (20-25°C)

HLB

15.6

Quality Level

200

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General description

Polyoxyethylenesorbitan monopalmitate, or TWEEN 40, is a non-ionic detergent.

Application

Non-ionic detergent used for cell lysis, nuclei isolation and cell fractionation.
Polyoxyethylenesorbitan monopalmitate, or TWEEN 40, has been used in a study to assess the determination of iodide in urine based on a chemiluminescence system. It has also been used in a study to investigate the delivery of astaxanthin and canthaxanthin to HepG2 cells.

Legal Information

TWEEN is a registered trademark of Croda International PLC

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCW5714
MKCW7097
MKCW2985
MKCV2740
MKCR4647

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Takamasa Kaneko et al.
Medical mycology, 44(3), 227-231 (2006-05-17)
We developed a simple identification kit for nine species of Malassezia (M. furfur, M. slooffiae, M. sympodialis, M. restricta, M. obtusa, M. globosa, M. pachydermatis, M. dermatis, and M. japonica) based on their biological features. This method utilizes Tween 40-based
Mohammad Reza Lornejad-Schäfer et al.
European journal of nutrition, 46(2), 79-86 (2007-01-18)
Carotenoids lutein and zeaxanthin are proposed to protect ocular tissues from free-radical damage that can cause cataract and age-related macular degeneration (AMD). They accumulate selectively in the lens and macular region of the retina. Changes in the retinal pigment epithelium
Matija Tomsic et al.
International journal of pharmaceutics, 327(1-2), 170-177 (2006-08-26)
Small-angle X-ray scattering technique has been used to study the structural properties of the quaternary microemulsion Tween 40/Imwitor 308/isopropyl myristate/water and of five-component system obtained by the addition of the drug ketoprofen to the original quaternary system. The results enlighten
Branka Rozman et al.
Drug delivery, 14(4), 235-245 (2007-05-15)
An interesting strategy for protecting skin from excessive exposure to free radicals is to support the skin endogenous antioxidant system. As the balance between different skin antioxidants is very important, a combined therapy using at least two antioxidants is desirable.
Sinead M O'Sullivan et al.
The British journal of nutrition, 91(5), 757-764 (2004-05-13)
Epidemiological evidence suggests that dietary intake of carotenoids and tocopherols may influence the risk of certain chronic diseases, such as cancer and CVD. In vitro studies investigating the synergistic effects of mixtures of carotenoids and tocopherols have been hindered due
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