P6628
Pilocarpine nitrate salt
≥98% (HPLC), muscarinic acetylcholine receptor agonist, powder
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Empirical Formula (Hill Notation):
C11H16N2O2 · HNO3
CAS Number:
Molecular Weight:
271.27
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
205-723-7
MDL number:
Beilstein/REAXYS Number:
4171406
Assay:
≥98% (HPLC)
Form:
powder
Product Name
Pilocarpine nitrate salt, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
optical activity
[α]25/D +83°, c = 10 in H2O(lit.)
color
white
solubility
H2O: 100 mg/mL
SMILES string
O[N+]([O-])=O.CC[C@H]1[C@H](COC1=O)Cc2cncn2C
InChI
1S/C11H16N2O2.HNO3/c1-3-10-8(6-15-11(10)14)4-9-5-12-7-13(9)2;2-1(3)4/h5,7-8,10H,3-4,6H2,1-2H3;(H,2,3,4)/t8-,10-;/m0./s1
InChI key
PRZXEPJJHQYOGF-GNAZCLTHSA-N
Gene Information
human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)
Application
Pilocarpine nitrate salt has been used to measure bronchoconstriction and M2 and M3 muscarinic receptor function in vivo. It has also been used to induce electrographic and behavioral seizures and to study the different patterns of neuronal activation and neurodegeneration in Proechimys rats and Wistar rats.
Biochem/physiol Actions
Nonselective muscarinic acetylcholine receptor agonist.
Nonselective muscarinic acetylcholine receptor agonist; used to produce an experimental model of epilepsy.
Pilocarpine is a cholinergic muscarinic agonist, useful in inducing epilepsy in animal models. It is specially used to study the pathogenesis of epileptogenesis and pharmacoresistant epilepsy. Pilocarpine application is more popular among the rat and mice models.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Ox. Sol. 2
Storage Class
5.1B - Oxidizing hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.