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P9180

Procaterol hydrochloride

β2 adrenoceptor agonist, powder

Synonym(s):

erythro-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-2(1H)-quinolinone

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About This Item

Empirical Formula (Hill Notation):
C16H22N2O3 · HCl
CAS Number:
62929-91-3
Molecular Weight:
326.82
NACRES:
NA.77
PubChem Substance ID:
24899017
UNSPSC Code:
12352202
EC Number:
263-763-0
MDL number:
MFCD04221378
Form:
powder
Quality level:
200
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Product Name

Procaterol hydrochloride,

form

powder

Quality Level

200

storage temp.

2-8°C

SMILES string

Cl.CC[C@H](NC(C)C)[C@H](O)c1ccc(O)c2NC(=O)C=Cc12

InChI

1S/C16H22N2O3.ClH/c1-4-12(17-9(2)3)16(21)11-5-7-13(19)15-10(11)6-8-14(20)18-15;/h5-9,12,16-17,19,21H,4H2,1-3H3,(H,18,20);1H/t12-,16+;/m0./s1

InChI key

AEQDBKHAAWUCMT-CVHDTDHSSA-N

Related Categories

General description

Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.

Biochem/physiol Actions

β2-adrenoceptor agonist; bronchodilator.

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

监管及禁止进口产品

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Certificates of Analysis (COA)

Lot/Batch Number
BCBZ8090
BCBN8424V
BCBJ5050V
1399480V
1399034

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Nobuyo Komatani-Tamiya et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 29(3-4), 511-522 (2012-04-18)
The beating cilia play a key role in lung mucociliary transport. The ciliary beating frequency (CBF) and ciliary bend amplitude (CBA) of isolated mouse bronchiolar ciliary cells were measured using a light microscope equipped with a high-speed camera (500 Hz).
Immune System Diseases: New Insights for the Healthcare Professional (2012)
Y Yamazaki et al.
British journal of pharmacology, 124(3), 593-599 (1998-07-01)
1. The beta-adrenoceptor (beta-AR) subtypes mediating relaxation of the rabbit, rat and canine detrusors were subjected to functional investigation using selective beta-AR agonists and antagonists. 2. In all three species, isoprenaline, noradrenaline and adrenaline each produced a concentration-dependent relaxation of
Masahiro Satake et al.
Arzneimittel-Forschung, 61(1), 8-13 (2011-03-02)
The purpose of this study was to evaluate the inhibitory effect of procaterol (procaterol hydrochloride, CAS 62929-91-3) on exercise dynamic lung hyperinflation during the 6-min walk test (6MWT) in stable chronic obstructive disease (COPD) patients. Fourteen patients with stable COPD
F Preitner et al.
British journal of pharmacology, 124(8), 1684-1688 (1998-10-02)
The beta3-adrenoceptor plays an important role in the adrenergic response of brown and white adipose tissues (BAT and WAT). In this study, in vitro metabolic responses to beta-adrenoceptor stimulation were compared in adipose tissues of beta3-adrenoceptor knockout and wild type
View All Related Papers

Global Trade Item Number

SKUGTIN
P9180-10MG04061834402626

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