P9180
Procaterol hydrochloride
β2 adrenoceptor agonist, powder
Synonym(s):
erythro-8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-2(1H)-quinolinone
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About This Item
Empirical Formula (Hill Notation):
C16H22N2O3 · HCl
CAS Number:
Molecular Weight:
326.82
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
263-763-0
MDL number:
Product Name
Procaterol hydrochloride,
InChI key
AEQDBKHAAWUCMT-CVHDTDHSSA-N
InChI
1S/C16H22N2O3.ClH/c1-4-12(17-9(2)3)16(21)11-5-7-13(19)15-10(11)6-8-14(20)18-15;/h5-9,12,16-17,19,21H,4H2,1-3H3,(H,18,20);1H/t12-,16+;/m0./s1
SMILES string
Cl.CC[C@H](NC(C)C)[C@H](O)c1ccc(O)c2NC(=O)C=Cc12
form
powder
storage temp.
2-8°C
Quality Level
Related Categories
General description
Procaterol is used to prevent lung fibroblast migration. It has anti-inflammatory properties. It can block type 2 T helper (Th2)-related chemokine production in human monocytes and bronchial epithelial cells.
Biochem/physiol Actions
β2-adrenoceptor agonist; bronchodilator.
Features and Benefits
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
监管及禁止进口产品
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Yukiko Hiraguchi et al.
International archives of allergy and immunology, 155 Suppl 1, 85-89 (2011-06-10)
Viral respiratory tract infections play an important role in the inception and exacerbation of asthma. Eosinophils, major effector cells in asthma, often accumulate in the airways during viral infections and are possibly activated by respiratory RNA viruses through Toll-like receptor
Ethanolamines: Advances in Research and Application (2012)
F Preitner et al.
British journal of pharmacology, 124(8), 1684-1688 (1998-10-02)
The beta3-adrenoceptor plays an important role in the adrenergic response of brown and white adipose tissues (BAT and WAT). In this study, in vitro metabolic responses to beta-adrenoceptor stimulation were compared in adipose tissues of beta3-adrenoceptor knockout and wild type
Masahiro Satake et al.
Arzneimittel-Forschung, 61(1), 8-13 (2011-03-02)
The purpose of this study was to evaluate the inhibitory effect of procaterol (procaterol hydrochloride, CAS 62929-91-3) on exercise dynamic lung hyperinflation during the 6-min walk test (6MWT) in stable chronic obstructive disease (COPD) patients. Fourteen patients with stable COPD
Jin Sakamoto et al.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 31(7), 773-779 (2012-04-27)
It is a matter of great importance in a donation after cardiac death to attenuate ischemia-reperfusion injury (IRI) related to the inevitable warm ischemic time. Donor dogs were rendered cardiac-dead and left at room temperature. The dogs were allocated into
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