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Merck
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PLA0076

Rabbit anti-WAPL Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

FOE, KIAA0261, WAPAL, WAPL cohesin release factor, friend of EBNA2, friend of EBNA2 (Epstein-Barr virus nuclear protein 2), friend of EBNA2 protein, wings apart-like homolog (Drosophila)

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
-

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

technique(s)

western blot: 1:10,000-1:25,000

accession no.

Q7Z5K2

UniProt accession no.

Q7Z5K2

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

rabbit ... WAPL(23063)

Immunogen

The epitope recognized by PLA0076 maps to a region between residues 1125 and 1175 of human wings apart like/KIAA0261 using the numbering given in TrEMBL entry Q7Z5K2 (GeneID 23063).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

Wings apart-like protein homolog (WAPL) is a cohesin binding protein that functions to destabilize cohesin-linked sister chromatids during prophase. Human WAPL has been shown to be highly expressed in cervical cancer and when over-expressed in mouse cells, induces tumorigenesis. WAPL was isolated in a screen for proteins that interact with Epstein-Barr nuclear protein 2 (EBNA2).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Lot/Batch Number
1

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