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Merck
CN

PLA0098

Rabbit anti-BIRC6/Apollon Antibody, Affinity Purified

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Synonym(s):

BIR repeat-containing ubiquitin-conjugating enzyme, BRUCE, apollon, baculoviral IAP repeat-containing 6, ubiquitin-conjugating BIR domain enzyme apollon, ubiquitin-conjugating BIR-domain enzyme apollon

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, IP, WB
Citations:
-

Key Documents

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biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

concentration

1 mg/mL

technique(s)

immunohistochemistry: 1:2,000- 1:10,000, immunoprecipitation (IP): 2-10 μg/mg, western blot: 1:2,000-1:10,000

accession no.

Q9NR09

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

100

Gene Information

rabbit ... BIRC6/Apollon(57448)

Immunogen

The epitope recognized by PLA0098 maps to a region between residue 4775 and the C-terminus (residue 4829) of human Baculoviral IAP repeat-containing protein 6 using the numbering given in Swiss-Prot entry Q9NR09 (GeneID 57448).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

BIRC6/Apollon contains a baculoviral-IAP repeat (BIR) and ubiquitin-conjugating enzyme (UBC) domain and functions in the inhibition of apoptosis. BIRC6/Apollon inhibits apoptosis by ubiquitinating and promoting the proteasomal degradation of SMAC (second mitochondria-derived activator of caspase) and caspase-9.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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