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PLA0206

Sigma-Aldrich

Rabbit anti-BCAR3 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):
NSP2, breast cancer antiestrogen resistance 3 protein, SH2D3B, SH2 domain-containing protein 3B, dJ1033H22.2 (breast cancer anti-estrogen resistance 3), novel SH2-containing protein 2
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human

concentration

0.2 mg/mL

technique(s)

immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_003558.1

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... BCAR3(8412)

Immunogen

The epitope recognized by PLA0206 maps to a region between residue 25 and 75 of human breast cancer anti-estrogen resistance 3 using the numbering given in entry NP_003558.1 (GeneID 8412).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

BCAR3 (breast cancer anti-estrogen resistance 3) was originally identified as a factor that confers resistance to anti-estrogens in breast cancer cells. BCAR3 contains a Ras-GEF domain and an SH2 domain. It is related to SHEP1 and NSP1 and is thought to also play a role as an adaptor protein that mediates integrin signaling to modulate cell adhesion and migration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

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