PD-1 (programmed death-1) is an immunosuppressive molecule, which is also known as PDCD1 (programmed cell death 1). It is located on chromosome 2q37.3. It is a member of immunoglobulin receptor superfamily.
a 16 amino acid peptide from near the carboxy-terminus of human PD-1.
PD-1 (programmed death-1) gene is sensitive to systemic lupus erythematosus (SLE). Polymorphisms in PD-1 may participate in the growth of EOC (epithelial ovarian cancer). It acts as a negative regulator of T cells. It is also responsible for immune escape mediated by tumor cell.
The action of this antibody can be blocked using blocking peptide SBP4065.
Solution in phosphate buffered saline containing 0.02% sodium azide
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