R5278
Anti-RAGE (Receptor for Advanced Glycation Endproducts) antibody produced in rabbit
affinity isolated antibody
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
15
biological source
rabbit
Quality Segment
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse, rat
technique(s)
immunohistochemistry: 1-2 μg/mL using transgenic mouse retina, western blot: 1 μg/mL using using mouse lung extract
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... AGER(177)
mouse ... Ager(11596)
rat ... Ager(81722)
General description
Receptor for advanced glycation end products (RAGE), also known as advanced glycosylation end-product specific receptor (AGER) is encoded by the gene mapped to human chromosome 6p21. The encoded protein is a member of the immunoglobulin superfamily of cell surface molecules.
Immunogen
synthetic peptide corresponding to amino acid residues 362-380 from rat RAGE. This sequence is 100% conserved in mouse and 70% conserved in human.
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)
Western Blotting (1 paper)
Anti-RAGE (Receptor for Advanced Glycation Endproducts) antibody produced in rabbit has been used in western blot and flow cytometry.
Biochem/physiol Actions
The soluble form of receptor for advanced glycation end products (RAGE) has a function in the Wnt pathway. RAGE has a role in the development of inflammatory and cellular damage, as well as cellular toxicity. It has been associated with diabetic atherosclerosis. AGER/RAGE also modulates cell proliferation, differentiation and apoptosis.{93
Physical form
Solution in phosphate buffered saline containing 1.0 mg/mL bovine serum albumin and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Still not finding the right product?
Try our Product Selector Tool to narrow your options
Storage Class
10 - Combustible liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.