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Merck
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SAB2501197

Anti-UBE2F (C-terminal) antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-MGC18120, Anti-NCE2, ubiquitin-conjugating enzyme E2F (putative)

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IHC, WB
Citations:
3
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biological source

goat

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, rat, human

technique(s)

immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Quality Level

Gene Information

human ... UBE2F(140739)

General description

Ubiquitin conjugating enzyme E2 F (UBE2F), also known as NEDD8-conjugating enzyme 2 (NCE2) or MGC18120, is encoded by the gene mapped to human chromosome 2q37.3.

Immunogen

Peptide with sequence CHLRDKEDFRNKVDD, from the C-Terminus of the protein sequence according to NP_542409.1.

Biochem/physiol Actions

Ubiquitin conjugating enzyme E2 F (UBE2F) acts as a neural precursor cell expressed, developmentally down-regulated 8 (NEDD8)-conjugating enzyme E2 in the neddylation cascade. It activates the polyubiquitin synthesis of cullin RING (really interesting new gene) ligase viral infectivity factor (CRL5Vif)-core binding factor β (CBFβ) complex in vitro.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

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Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair.
Chung d and Dellaire G
Biomolecules (2015)
What was the set of ubiquitin and ubiquitin-like conjugating enzymes in the eukaryote common ancestor?
Michelle C
Journal of Molecular Evolution (2009)
Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G.
Stanley DJ
PLoS Pathogens (2012)

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